ArticleIndian journal of dermatology
Hypothesis: zinc can be effective in treatment of vitiligo.
Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Zinc, copper, and selenium levels in vitiligo: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Oxidative Stress and Potential Antioxidant Therapies in Vitiligo: A Narrative Review.Molecular diagnosis & therapy · 2023Review
- Article
- Serum Copper and Zinc Levels Among Iranian Vitiligo Patients.Dermatology practical & conceptual · 2022Article
- Interactions between ZnO Nanoparticles and Polyphenols Affect Biological Responses.Nanomaterials (Basel, Switzerland) · 2022Article
- Diet and Vitiligo: The Story So Far.Cureus · 2022Review
- Serum Zinc and Inflammatory Cytokines in Vitiligo.The Journal of clinical and aesthetic dermatology · 2020Article
- Are Patients with Vitiligo More Prone to Myocardial Infarction?: A Case-control Study.The Journal of clinical and aesthetic dermatology · 2019Article
- Unconventional Treatments for Vitiligo: Are They (Un) Satisfactory?Open access Macedonian journal of medical sciences · 2018Review
- Protective Effect of Increased Zinc Supply against Oxidative Damage of Sublingual Gland in Chronic Exposure to Cadmium: Experimental Study on Rats.Oxidative medicine and cellular longevity · 2018Article
- Evaluation of the serum zinc level in patients with vitiligo.Postepy dermatologii i alergologii · 2017Article
- Highlights in pathogenesis of vitiligo.World journal of clinical cases · 2015Review
- Zinc therapy in dermatology: a review.Dermatology research and practice · 2014Review
- The Newest Hypothesis about Vitiligo: Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein.ISRN dermatology · 2012Article
- Serum Zinc Level in Vitiligo: A Case-control Study.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitiligo is a common depigmenting skin disorder (prevalence 0.1-2%), still represents a cause of stigmatization and quality of life impairment in a large population. Several theories on vitiligo etiopathogenesis have been suggested including in trauma, stress, and autoimmune and genetic predisposition, accumulation of toxic compounds, altered cellular environment, imbalance in the oxidant-antioxidant system, impaired melanocyte migration and/or proliferation, infection, and psychological factors. Zinc, as a trace element, has many vital functions in human. It is antiapoptotic factor and needed as a cofactor for antioxidant defense system. It plays an important role in the process of melanogenesis. It may be effective in prevention and treatment of vitiligo via some mechanism. Herein, we suggested some probable protective mechanism for zinc in association with vitiligo.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.