Evidence map›Paper›PMID 22120510›Full record

ReviewSeminars in cell & developmental biology2012

Unravelling global genome organization by 3C-seq.

Hideki Tanizawa, Ken-ichi Noma

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. The Evolution of Next-Generation Sequencing Technologies.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
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  12. Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  13. Epigenetic mechanisms and the development of asthma.The Journal of allergy and clinical immunology · 2012
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hideki TanizawaThe Wistar Institute, Philadelphia, PA, USA.
Ken-ichi Noma

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Alessandro Gardini · 1985 to 2026
$75.9M
A New Methodology to Decipher Three-Dimensional Genome StructureDP2OD004348 · OD · WISTAR INSTITUTE · PI NOMA, KENICHI · 2008 to 2008
$3.1M
NCI NIH HHS CA010815NCI NIH HHS P30 CA010815NIH HHS DP2 OD004348
6 · The paper itself

Abstract

Eukaryotic genomes exist in the cell nucleus as an elaborate three-dimensional structure which reflects various nuclear processes such as transcription, DNA replication and repair. Next-generation sequencing (NGS) combined with chromosome conformation capture (3C), referred to as 3C-seq in this article, has recently been applied to the yeast and human genomes, revealing genome-wide views of functional associations among genes and their regulatory elements. Here, we compare the latest genomic approaches such as 3C-seq and ChIA-PET, and provide a condensed overview of how eukaryotic genomes are functionally organized in the nucleus.

Indexed as

Chromosome PositioningGenome, FungalGenome, HumanNucleic Acid ConformationCell NucleusChromosome MappingChromosomes, FungalChromosomes, HumanDNA, FungalGenomicsHumansSequence Analysis, DNAYeastsDNA, Fungal

Identifiers

PMID22120510
PMCPMC3362197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.