Evidence map›Paper›PMID 22120113›Full record

ArticleThe Journal of infection2012

Seroprevalence of and risk factors for Toscana and Sicilian virus infection in a sample population of Sicily (Italy).

Giuseppe Calamusa, Rosalia Maria Valenti, Francesco Vitale, Caterina Mammina, Nino Romano, James Jerome Goedert, Gianni Gori-Savellini, Maria Grazia Cusi, Emanuele Amodio

Abstract read
In one paragraph

Article in The Journal of infection, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Human neuroinvasive Toscana virus infections in Italy from 2016 to 2023: Increased incidence in 2022 and 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Human seroprevalence of Toscana virus and Sicilian phlebovirus in the southwest of Portugal.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Taking a bite out of nutrition and arbovirus infection.PLoS neglected tropical diseases · 2018
    Review
  15. Article
  16. Article
  17. Immunoglobulin M seropositivity for Toscana virus in a random population sample in Sicily.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giuseppe CalamusaDepartment of Sciences for Health Promotion, G. D'Alessandro, University of Palermo, Via Del Vespro n°133, cap 90127, Italy.
Rosalia Maria Valenti
Francesco Vitale
Caterina Mammina
Nino Romano
James Jerome Goedert
Gianni Gori-Savellini
Maria Grazia Cusi
Emanuele Amodio

Funding

Microbes and Human MalignanciesZIACP010214 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI VOGTMANN, EMILY · 2010 to 2021
$5.5M
Intramural NIH HHS ZIA CP010214
6 · The paper itself

Abstract

objectiveThe present study aimed to assess seroprevalence of and risk factors for Toscana (TOSV) and Sicilian (SFSV) virus infections in a sample of Sicilian subjects.

methodsA cross-sectional seroepidemiological study was conducted on 271 individuals. Each participant completed a self-administrated questionnaire and provided a serum sample which was analyzed for the presence of IgG specific anti-TOSV and anti-SFSV viruses.

resultsOverall, 90 subjects (33.2%) were positive for TOSV IgG, 25 (9.2%) were positive for SFSV IgG and 11 (4%) were positive for both the viruses. A higher risk for TOSV seropositivity was found in participants who were older (adjOR = 1.02 per year; 95% CI = 1.01-1.03), having a pet living outdoors (adjOR = 2.62; 95% CI = 1.42-4.83) and being obese (adjOR = 2.37; 95% CI = 1.06-5.30).

conclusionsTOSV seroprevalence appears to be relatively high in Sicilian general population, especially in older adults, representing a potential public health concern. The observations that seropositivity for TOSV was not significantly associated with SFSV seropositivity, and none of the risk factors associated with TOSV were associated with SFSV seem to suggest that these two phleboviruses may have different ecology and transmission pathways.

Indexed as

AdolescentAdultAgedAged, 80 and overAntibodies, ViralChildChild, PreschoolCross-Sectional StudiesFemaleHumansItalyMaleMiddle AgedPhlebotomus FeverPhlebovirusPublic HealthAntibodies, Viral

Identifiers

PMID22120113
PMCPMC3630500

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.