Evidence map›Paper›PMID 22118666›Full record

ArticleChemistry & biology2011

Mitochondrial complex III: Tuner of autophagy.

Shengkan Jin

Abstract readComment
In one paragraph

Article in Chemistry & biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Shengkan JinPharmacology Department, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA. jinsh@umdnj.edu

Funding

The Role of Autophagy in the Age-related Mitochondrial DeteriorationR01AG030081 · NIA · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI JIN, SHENGKAN VICTOR · 2008 to 2011
$1.0M
The Role of Autophagy in TumorigenesisR01CA116088 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI JIN, SHENGKAN VICTOR · 2007 to 2010
$874k
NCI NIH HHS R01 CA116088NIA NIH HHS R01 AG030081
6 · The paper itself

Abstract

Using chemical approaches, Ma et al. in this issue of Chemistry & Biology identify mitochondrial complex III as a specific positive regulator of autophagy. This study brings us a step closer to understanding the mechanism by which basal autophagy is coupled to cellular energy flux.

Identifiers

PMID22118666
PMCPMC13101080

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.