Evidence map›Paper›PMID 22118283›Full record

ArticleMethods in cell biology2011

Cell identification and cell lineage analysis.

Claudiu A Giurumescu, Andrew D Chisholm

Abstract read
In one paragraph

Article in Methods in cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Claudiu A GiurumescuSection of Cell and Developmental Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Andrew D Chisholm

Funding

Mechanisms of Tissue Morphogenesis in C. elegansR01GM054657 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CHISHOLM, ANDREW D · 1997 to 2018
$5.8M
Quantitative analysis of morphogenetic processes at single cell resolution.F32GM090652 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIURUMESCU, CLAUDIU ADRIAN · 2010 to 2010
$50k
NIGMS NIH HHS F32 GM090652NIGMS NIH HHS GM54657NIGMS NIH HHS R01 GM054657
6 · The paper itself

Abstract

Caenorhabditis elegans is uniquely suited to the analysis of cell lineage patterns. C. elegans has a small number of somatic cells whose position and morphology are almost invariant from animal to animal. Because C. elegans is virtually transparent, cells can be identified in live animals using a simple bright-field microscopy technique, Nomarski differential interference contrast (DIC), or by expression of transgenic fluorescent reporter genes. The small size and rapid development of C. elegans mean that animals can develop while under continuous observation, allowing cell lineages to be analyzed throughout embryonic and postembryonic development. Embryonic cell lineages can also be traced semiautomatically using timelapse imaging of GFP-labeled nuclei. Analysis of mutant cell lineages remains important for defining the roles of developmental control genes.

Indexed as

Cell LineageAnimalsCaenorhabditis elegansCell DifferentiationCell DivisionEmbryo, NonmammalianGene ExpressionGenes, ReporterMicroscopy, InterferencePhenotypeTerminology as Topic

Identifiers

PMID22118283
PMCPMC4410678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.