ReviewEye (London, England)2012
Diagnostic dilemmas in retinitis and endophthalmitis.
Review in Eye (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Evaluation of the vitreous microbial contamination rate in office-based three-port microincision vitrectomy surgery using Retrector technology.BMC ophthalmology · 2014Trial
- Bilateral Panuveitis and Placoid Retinitis in Ocular Syphilis Complicated by Subsequent Retinal Detachment.Journal of vitreoretinal diseases · 2026Article
- Clinical Assessment of a Highly Multiplexed Panel Assay for the Diagnosis of Infectious Uveitis.American journal of ophthalmology · 2026Article
- Areas of uncertainty in endophthalmitis care.World journal of clinical cases · 2026Review
- PresumedFrontiers in medicine · 2026Article
- Endogenous endophthalmitis secondary to Lemierre's Syndrome originating from pharyngotonsillitis.Journal of ophthalmic inflammation and infection · 2024Article
- [Bacterial endogenous endophthalmitis : Spectrum of pathogens and drug therapy].Die Ophthalmologie · 2024Review
- Multitask Deep Learning for Joint Detection of Necrotizing Viral and Noninfectious Retinitis From Common Blood and Serology Test Data.Investigative ophthalmology & visual science · 2024Article
- An All-in-One Highly Multiplexed Diagnostic Assay for Rapid, Sensitive, and Comprehensive Detection of Intraocular Pathogens.American journal of ophthalmology · 2023Article
- Pars-plana-vitrectomy for endophthalmitis treatment and the role of standardized ultrasound.International ophthalmology · 2023Article
- Challenges in the diagnosis and management of simultaneous, bilateral, toxic anterior segment syndrome after phacorefractive surgery.Digital journal of ophthalmology : DJO · 2023Article
- Clinical and Virological Characteristics and Prognostic Factors in Viral Necrotizing Retinitis.Journal of personalized medicine · 2022Article
- Severe Retinal Necrosis Due to Klebsiella pneumoniae After Acute Prostatitis.The American journal of case reports · 2022Article
- Endogenous Endophthalmitis-The Clinical Significance of the Primary Source of Infection.Journal of clinical medicine · 2022Review
- A case of endogenous candida endophthalmitis with incidental cytomegalovirus infection and optic neuropathy in a patient recovered from severe COVID-19.Indian journal of ophthalmology · 2022Article
- Fungal Endophthalmitis: A Comprehensive Review.Journal of fungi (Basel, Switzerland) · 2021Review
- A Case of Chorioretinitis with Retinal Angiomatous Proliferation.Case reports in ophthalmological medicine · 2021Article
- Diagnostic vitrectomy for infectious uveitis.International ophthalmology clinics · 2014Review
- Current concepts and future directions in the pathogenesis and management of non infectious uveitis.Eye (London, England) · 2012Article
- Vitreous analysis in the management of uveitis.Mediators of inflammation · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Visual loss in infectious posterior uveitis or panuveitis can occur if proper therapy is delayed because of diagnostic uncertainty. Some disorders, such as acute retinal necrosis and bacterial endophthalmitis, can be rapidly progressive, and therefore require prompt and accurate diagnosis to guide initial therapy. Other more slowly evolving infections, such as toxoplasmic chorioretinitis or fungal endophthalmitis, can be worsened by empiric use of corticosteroids without specific antimicrobial coverage. Key ocular diagnostic features are helpful but highly variable with overlap with both non-infectious uveitis and neoplastic masquerades, even for key signs such as hypopyon. Close examination of the fundus with attention to color, location, size, border, and opacity of lesions and associated arteriolitis or frosted branch angiitis is helpful in the diagnosis of chorioretinitis. Ultrasonography is an important tool in the evaluation of eyes with suspected endophthalmitis, especially those with intracapsular infection or focal infected deposits. Testing of intraocular fluid can be extremely useful but suffers from inaccessibility, poor sensitivity, and test selections dependent on a presumptive diagnosis, which may be wrong. The dilemma for clinician is to make the correct diagnosis of a rare, blinding, variegated disease quickly enough to intercede with specific therapy or to apply empiric therapy in a sufficiently skilled manner to avert disaster and confirm the diagnosis by response to treatment. When non-infectious uveitis is in the differential, empiric corticosteroids must sometimes be used, at great risk, if clinical examination, ancillary testing, and any available intraocular diagnostic tests have failed to confirm a diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.