ReviewJournal of biosciences2011
Cancer stem cell hypotheses: impact on modern molecular physiology and pharmacology research.
Review in Journal of biosciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Cancer stem cells and macrophages: molecular connections and future perspectives against cancer.Oncotarget · 2021Review
- Histone Deacetylase Modifications by Probiotics in Colorectal Cancer.Journal of gastrointestinal cancer · 2020Review
- Comparison of Tumor- and Bone Marrow-Derived Mesenchymal Stromal/Stem Cells from Patients with High-Grade Osteosarcoma.International journal of molecular sciences · 2018Article
- Biological markers of prognosis, response to therapy and outcome in ovarian carcinoma.Expert review of molecular diagnostics · 2016Review
- A new insight into cancer stem cell markers: Could local and circulating cancer stem cell markers correlate in colorectal cancer?Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Major Protein of Carcinoembryonic Antigen Gene Family - CD66c, A Novel Marker in Colon Carcinoma.Journal of clinical and diagnostic research : JCDR · 2016Article
- MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown.Journal of hematology & oncology · 2015Review
- Prognostic value of cancer stem cell marker CD133 in ovarian cancer: a meta-analysis.International journal of clinical and experimental medicine · 2015Review
- Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma.BMC cancer · 2014Article
- Nodal promotes the self-renewal of human colon cancer stem cells via an autocrine manner through Smad2/3 signaling pathway.BioMed research international · 2014Article
- Colon cancer stem cells: controversies and perspectives.World journal of gastroenterology · 2013Review
- Arsenic trioxide inhibits viability of pancreatic cancer stem cells in culture and in a xenograft model via binding to SHH-Gli.OncoTargets and therapy · 2013Article
- Staying alive: metabolic adaptations to quiescence.Cell cycle (Georgetown, Tex.) · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although questioned on several occasions, the existence of cancer stem cells (CSCs) has been confirmed by a number of studies on experimental animal models. Nevertheless, it was shown that CSC hypotheses have several limitations and inconsistencies regarding the explanation of CSC origin, CSC identification and isolation, possible heterogeneity within CSC population, as well as methodology issues in some studies that were carried out in order to prove CSC existence. The aim of this article is to give a short and comprehensive review of recent advances concerning CSC hypothesis and to describe its impact on modern molecular physiology and pharmacology research.
Indexed as
Identifiers
22116294What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.