ArticleJournal of bacteriology1990
Trigger factor depletion or overproduction causes defective cell division but does not block protein export.
Article in Journal of bacteriology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 122 citations in OpenAlex.
- Article
- Omics-based analysis ofMicrobiome research reports · 2024Article
- Article
- Trigger factor is a bona fide secretory pathway chaperone that interacts with SecB and the translocase.EMBO reports · 2020Article
- Protein Transport Across the Bacterial Plasma Membrane by the Sec Pathway.The protein journal · 2019Review
- Multitasking of Hsp70 chaperone in the biogenesis of bacterial functional amyloids.Communications biology · 2018Article
- Protein export through the bacterial Sec pathway.Nature reviews. Microbiology · 2017Review
- Analysis of Spo0M function in Bacillus subtilis.PloS one · 2017Article
- Multitasking SecB chaperones in bacteria.Frontiers in microbiology · 2014Review
- Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo.Cell · 2011Article
- Role of SufI (FtsP) in cell division of Escherichia coli: evidence for its involvement in stabilizing the assembly of the divisome.Journal of bacteriology · 2007Article
- Global analysis of host response to induction of a latent bacteriophage.BMC microbiology · 2007Article
- A homolog of Bacillus subtilis trigger factor in Listeria monocytogenes is involved in stress tolerance and bacterial virulence.Applied and environmental microbiology · 2006Article
- A little help from my friends: quality control of presecretory proteins in bacteria.Journal of bacteriology · 2004Review
- Functional dissection of Escherichia coli trigger factor: unraveling the function of individual domains.Journal of bacteriology · 2004Article
- In vivo analysis of the overlapping functions of DnaK and trigger factor.EMBO reports · 2004Article
- Disruption of the genes for ClpXP protease in Salmonella enterica serovar Typhimurium results in persistent infection in mice, and development of persistence requires endogenous gamma interferon and tumor necrosis factor alpha.Infection and immunity · 2001Article
- Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome.Microbiology and molecular biology reviews : MMBR · 2000Review
- Assisted folding of D-glyceraldehyde-3-phosphate dehydrogenase by trigger factor.Protein science : a publication of the Protein Society · 2000Article
- Overexpression of trigger factor prevents aggregation of recombinant proteins in Escherichia coli.Applied and environmental microbiology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Trigger factor is an abundant cytosolic protein of Escherichia coli which can stabilize proOmpA for in vitro translocation across inner membrane vesicles. The gene encoding E. coli trigger factor was isolated and sequenced, allowing construction of strains in which the expression of trigger factor is readily regulated. We found no defect in the in vivo rate of synthesis or secretion of proOmpA in trigger factor-depleted cells. The primary physiological defect in trigger factor-depleted or -overproducing cells is an enrichment of filamented cells. Filamentation of the trigger factor-overproducing strain is suppressed by a multicopy plasmid expressing the essential division gene ftsZ, suggesting that trigger factor has an important role in cell division.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.