ReviewCanadian journal of gastroenterology = Journal canadien de gastroenterologie2011
The pathophysiology of chronic constipation.
Review in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Effectiveness of Caffeine in Reducing Constipation in Adults: A Systematic Review.International urogynecology journal · 2025Pooled it
- Global prevalence of constipation in older adults: a systematic review and meta-analysis.Wiener klinische Wochenschrift · 2023Pooled it
- Interventions for preventing postpartum constipation.The Cochrane database of systematic reviews · 2020Pooled it
- Interventions for preventing postpartum constipation.The Cochrane database of systematic reviews · 2015Pooled it
- Efficacy of auriculotherapy for constipation in adults: a systematic review and meta-analysis of randomized controlled trials.Journal of alternative and complementary medicine (New York, N.Y.) · 2014Pooled it
- Efficacy and safety of elobixibat in patients with chronic constipation-A randomized, multicenter, double-blind, placebo-controlled, parallel-group study from India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Trial
- Pelvic floor physical therapy in patients with chronic anal fissure: a randomized controlled trial.Techniques in coloproctology · 2022Trial
- Comparisons between Manual Lymph Drainage, Abdominal Massage, and Electrical Stimulation on Functional Constipation Outcomes: A Randomized, Controlled Trial.International journal of environmental research and public health · 2020Trial
- Trial
- Prebiotic UG1601 mitigates constipation-related events in association with gut microbiota: A randomized placebo-controlled intervention study.World journal of gastroenterology · 2019Trial
- Constipation with bloating: a clinical approach to evaluation and management.Annals of medicine · 2026Review
- Combined Colon Hydrotherapy and Catgut Embedding at the Fujie (SP14) Acupoint for Treating Slow Transit Constipation: a clinical efficacy and safety study.Journal of pharmacopuncture · 2026Article
- Early detection of opioid-induced constipation in patients initiating weak opioids for chronic non-cancer pain.Scientific reports · 2026Article
- Ileal bile acid transporter inhibitors for chronic constipation in the elderly.World journal of gastrointestinal pharmacology and therapeutics · 2026Article
- Differences in the Effectiveness of Uridine andPharmaceuticals (Basel, Switzerland) · 2025Article
- Association between blood lead levels and constipation in adults: insights from NHANES data (2005-2010).BMC gastroenterology · 2025Article
- Clinical Yield of Colonoscopy in Evaluation of Young Women with Constipation: An Age- and Gender-Based Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Prospective association of daily toothbrushing frequency and the prevalence of childhood functional constipation: the Japan Environment and Children's Study.Scientific reports · 2025Article
- A Hard Problem: Managing Constipation in the Geriatric Population.HCA healthcare journal of medicine · 2025Review
- Comparative efficacy of extra virgin olive oil versus refined olive oil in the treatment of individuals suffering from constipation: A double-blind randomized clinical trial study.Caspian journal of internal medicine · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent stools, difficult stool passage or both. The common approach to the pathophysiology of constipation groups the disorder into primary and secondary causes. Primary causes are intrinsic problems of colonic or anorectal function, whereas secondary causes are related to organic disease, systemic disease or medications. The normal process of colonic transit and defecation is discussed, and the etiology of constipation is reviewed.
Indexed as
Identifiers
22114753PMC3206564What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.