ArticleFrontiers in genetics2011
Implications of microRNAs in colorectal cancer development, diagnosis, prognosis, and therapeutics.
Article in Frontiers in genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Exosome-Mediated miR-21 Was Involved in the Promotion of Structural and Functional Recovery Effect Produced by Electroacupuncture in Sciatic Nerve Injury.Oxidative medicine and cellular longevity · 2022Article
- miR-330 Regulates Colorectal Cancer Oncogenesis by Targeting BACH1.Advanced pharmaceutical bulletin · 2020Article
- Clinicopathological and Prognostic Characteristics of RAD51 in Colorectal Cancer.Medicina (Kaunas, Lithuania) · 2020Article
- miR-381 Mediates the Development of Head and Neck Squamous Cell Carcinoma via Targeting STC2.OncoTargets and therapy · 2020Article
- Article
- miR-133b reverses cisplatin resistance by targeting GSTP1 in cisplatin-resistant lung cancer cells.International journal of molecular medicine · 2018Article
- Development of novel miR-129 mimics with enhanced efficacy to eliminate chemoresistant colon cancer stem cells.Oncotarget · 2018Article
- Article
- Article
- MiR-381 functions as a tumor suppressor in colorectal cancer by targeting Twist1.OncoTargets and therapy · 2016Article
- miR-659-3p is involved in the regulation of the chemotherapy response of colorectal cancer via modulating the expression of SPHK1.American journal of cancer research · 2016Article
- MiR-181b regulates cisplatin chemosensitivity and metastasis by targeting TGFβR1/Smad signaling pathway in NSCLC.Scientific reports · 2015Article
- miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase.Molecular oncology · 2014Article
- miR-181b as a key regulator of the oncogenic process and its clinical implications in cancer (Review).Biomedical reports · 2014Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
MicroRNAs (miRNAs) are a class of non-coding small RNAs with critical regulatory functions as post-transcriptional regulators. Due to the fundamental importance and broad impact of miRNAs on multiple genes and pathways, dysregulated miRNAs have been associated with human diseases, including cancer. Colorectal cancer (CRC) is among the most deadly diseases, and miRNAs offer a new frontier for target discovery and novel biomarkers for both diagnosis and prognosis. In this review, we summarize the recent advancement of miRNA research in CRC, in particular, the roles of miRNAs in CRC stem cells, epithelial-to-mesenchymal transition, chemoresistance, therapeutics, diagnosis, and prognosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.