Evidence map›Paper›PMID 22113348›Full record

ArticleAge (Dordrecht, Netherlands)2013

Fatigability as a function of physical activity energy expenditure in older adults.

Maciej S Buchowski, Sandra F Simmons, Lauren E Whitaker, James Powers, Linda Beuscher, Leena Choi, T Alp Ikizler, Kong Chen, John F Shnelle

Abstract readComparative Study
In one paragraph

Article in Age (Dordrecht, Netherlands), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Validation of the Pittsburgh Performance Fatigability Index in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  4. Article
  5. Article
  6. Evaluating Test-Retest Reliability of Fatigability in Chronic Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021
    Article
  7. Aerobic capacity and fatigability are associated with activity levels in women with hip osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Evaluation of two fatigability severity measures in elderly adults.Journal of the American Geriatrics Society · 2012
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Maciej S BuchowskiEnergy Balance Laboratory, Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University, 1161 21st Avenue South, Nashville, TN 37232, USA. maciej.buchowski@vanderbilt.edu
Sandra F Simmons
Lauren E Whitaker
James Powers
Linda Beuscher
Leena Choi
T Alp Ikizler
Kong Chen
John F Shnelle
Vanderbilt University · USGeriatric Research Education and Clinical Center · USNational Institutes of Health · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Development of obesity and metabolic clinical research programsZIADK071014 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI CHEN, KONG · 2009 to 2025
$12.3M
Metabolic Research Core: energy balance and obesity studiesZICDK071013 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI CHEN, KONG · 2009 to 2025
$12.3M
NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

Increased fatigue is a predictor of morbidity and mortality in older adults. Fatigability defines a change in performance or self-reported fatigue in response to physical activity (PA). However, the relationship of fatigability to PA-related energy expenditure (PAEE) is unknown. Changes in performance, fatigue, and energy expenditure were measured simultaneously in 17 adults (11 females, 74-94 years old) performing eight standardized PA tasks with various energy expenditure requirements in a whole-room indirect calorimeter. Change in performance was objectively measured using a PA movement monitor and change in fatigue was self-reported on a seven-point scale for each task. Performance and perceived fatigability severity scores were calculated as a ratio of change in performance and fatigue, respectively, and PAEE. We found that change in both objective performance and self-reported fatigue were associated with energy expenditure (Spearman rho = -0.72 and -0.68, respectively, p < 0.001) on a task requiring relatively high level of energy expenditure. The performance and perceived fatigability severity scores were significantly correlated (rho = 0.77, p < 0.001) on this task. In summary, results of this proof of concept pilot study show that both perceived and performance fatigability severity scores are related to PAEE-induced fatigue on a task requiring relatively high level of energy expenditure. We conclude that fatigability severity is a valid measure of PAEE-induced fatigue in older adults.

Indexed as

AgedAged, 80 and overAgingCalorimetry, IndirectEnergy MetabolismExerciseFatigueFemaleFollow-Up StudiesHumansMaleMotor ActivityPilot Projects

Identifiers

PMID22113348
PMCPMC3543733
OpenAlexW2084994398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.