Evidence map›Paper›PMID 22112997›Full record

ReviewCurrent opinion in pulmonary medicine2012

Computed tomography scans in severe asthma: utility and clinical implications.

Carolina Walker, Sumit Gupta, Ruth Hartley, Christopher E Brightling

Abstract readReview
In one paragraph

Review in Current opinion in pulmonary medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Holy Grail: the journey towards disease modification in asthma.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  5. Article
  6. Article
  7. Fetal Origins of Asthma: A Longitudinal Study from Birth to Age 36 Years.American journal of respiratory and critical care medicine · 2020
    Article
  8. Article
  9. Imaging of Airway Obstruction in Children.Frontiers in pediatrics · 2020
    Review
  10. Observational
  11. Article
  12. The role of imaging in the assessment of severe asthma.Current opinion in pulmonary medicine · 2017
    Review
  13. Article
  14. Article
  15. Review
  16. Should lung biopsies be performed in patients with severe asthma?European respiratory review : an official journal of the European Respiratory Society · 2015
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carolina WalkerDepartment of Infection, Institute for Lung Health, Immunity & Inflammation, University of Leicester, Leicester, UK.
Sumit Gupta
Ruth Hartley
Christopher E Brightling
University of Leicester · GB

Funding

Wellcome Trust 082265
6 · The paper itself

Abstract

purpose of reviewAsthma is a global burden, affecting 5% of the general adult population, of whom approximately 5-10% suffer from severe asthma. Severe asthma is a complex heterogeneous disease entity, with high morbidity and mortality. Increasingly novel techniques in computed tomography (CT) are being used to understand the pathophysiology of severe asthma. The utility and clinical implications of these CT techniques are the focus of this review. RECENT

findingsNovel qualitative and quantitative CT imaging techniques have enabled us to study the large airway architecture in detail, assess the small airway structure, and perform functional analysis of regional ventilation. SUMMARY: Despite advances in CT imaging techniques, there is an urgent need for both proof-of-concept studies and large cross-sectional and longitudinal clinical trials in severe asthma to validate and clinically correlate imaging derived measures. This will extend our current understanding of the pathophysiology of severe asthma, and unravel the structure-function relationship, with the potential to discover novel severe asthma phenotypes and predict mortality, morbidity, and response to existing and novel pharmacological and nonpharmacological therapies.

Indexed as

Tomography, X-Ray ComputedAirway RemodelingAsthmaHumansLungPredictive Value of TestsSeverity of Illness Index

Identifiers

PMID22112997
PMCPMC3387553
OpenAlexW2038178527

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.