ArticleNano reviews2010
Gold nanoparticles delivery in mammalian live cells: a critical review.
Article in Nano reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Microwave synthesis of ultrasmall gold nanoparticles, their γ-globulin interaction and subsequent effects in hepatocellular carcinoma cells.BMC chemistry · 2026Article
- Development of Biological-Window-Active Au Open-Shell Nanoparticles with High-Sensitivity Surface-Enhanced Raman Scattering Imaging Probe Properties.Nanomaterials (Basel, Switzerland) · 2026Article
- Impacts of loading thymoquinone to gold or silver nanoparticles on the efficacy of anti-tumor treatments in breast cancer with or without chemotherapeutic cisplatin.BMC biotechnology · 2025Article
- Regulation of Cell-Nanoparticle Interactions through Mechanobiology.Nano letters · 2025Article
- Improving the use of CRISPR/Cas9 gene editing machinery as a cancer therapeutic tool with the help of nanomedicine.3 Biotech · 2025Review
- Exploring Advanced CRISPR Delivery Technologies for Therapeutic Genome Editing.Small science · 2024Article
- Potential of Nano-Engineered Stem Cells in the Treatment of Multiple Sclerosis: A Comprehensive Review.Cellular and molecular neurobiology · 2023Review
- Treasure on the Earth-Gold Nanoparticles and Their Biomedical Applications.Materials (Basel, Switzerland) · 2022Review
- Digital research data: from analysis of existing standards to a scientific foundation for a modular metadata schema in nanosafety.Particle and fibre toxicology · 2022Review
- Exploiting the efficacy of Tyro3 and folate receptors to enhance the delivery of gold nanoparticles into colorectal cancer cellsNanoscale advances · 2021Article
- Influences of Dispersions' Shapes and Processing in Magnetic Field on Thermal Conductibility of PDMS-FeMaterials (Basel, Switzerland) · 2021Article
- Nanoparticle-based fluorescence probe for detection of NF-κB transcription factor in single cell via steric hindrance.Mikrochimica acta · 2021Article
- Size-Dependent Penetration of Gold Nanoprobes into Fixed Cells.ACS omega · 2021Article
- Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing.Frontiers in genetics · 2021Review
- Bioaccumulation dynamics and gene regulation in a freshwater bivalve after aqueous and dietary exposures to gold nanoparticles and ionic gold.Environmental science and pollution research international · 2020Article
- Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery.Molecules (Basel, Switzerland) · 2020Review
- Brain Targeted Gold Liposomes Improve RNAi Delivery for Glioblastoma.International journal of nanomedicine · 2020Article
- Warfarin-Capped Gold Nanoparticles: Synthesis, Cytotoxicity, and Cellular Uptake.Molecules (Basel, Switzerland) · 2019Article
- NanoTouch: intracellular recording using transmembrane conductive nanoparticles.Journal of neurophysiology · 2019Article
- Selective photothermal killing of cancer cells using LED-activated nucleus targeting fluorescent carbon dots.Nanoscale advances · 2019Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Functional nanomaterials have recently attracted strong interest from the biology community, not only as potential drug delivery vehicles or diagnostic tools, but also as optical nanomaterials. This is illustrated by the explosion of publications in the field with more than 2,000 publications in the last 2 years (4,000 papers since 2000; from ISI Web of Knowledge, 'nanoparticle and cell' hit). Such a publication boom in this novel interdisciplinary field has resulted in papers of unequal standard, partly because it is challenging to assemble the required expertise in chemistry, physics, and biology in a single team. As an extreme example, several papers published in physical chemistry journals claim intracellular delivery of nanoparticles, but show pictures of cells that are, to the expert biologist, evidently dead (and therefore permeable). To attain proper cellular applications using nanomaterials, it is critical not only to achieve efficient delivery in healthy cells, but also to control the intracellular availability and the fate of the nanomaterial. This is still an open challenge that will only be met by innovative delivery methods combined with rigorous and quantitative characterization of the uptake and the fate of the nanoparticles. This review mainly focuses on gold nanoparticles and discusses the various approaches to nanoparticle delivery, including surface chemical modifications and several methods used to facilitate cellular uptake and endosomal escape. We will also review the main detection methods and how their optimum use can inform about intracellular localization, efficiency of delivery, and integrity of the surface capping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.