ArticleDermato-endocrinology2011
A review of the role of solar ultraviolet-B irradiance and vitamin D in reducing risk of dental caries.
Article in Dermato-endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03158155 (Prevalence of Early Childhood Caries in Egyptian Children With Serum Vitamin D Deficiency.), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of Early Childhood Caries in Egyptian Children With Serum Vitamin D Deficiency.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis.Oral health & preventive dentistry · 2024Pooled it
- Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Prenatal or Childhood Serum Levels of Vitamin D and Dental Caries in Paediatric Patients: A Systematic Review.Oral health & preventive dentistry · 2020Pooled it
- Trial
- Vitamin D deficiency and oral health in the Middle East and North Africa (MENA): A public health perspective.Journal of Taibah University Medical Sciences · 2026Review
- Natural Light Exposure as a Potential 7th Pillar of Lifestyle Medicine.American journal of lifestyle medicine · 2026Article
- Vitamin D - a forgotten preventive agent against caries? A narrative review.Clinical oral investigations · 2025Review
- From cultural dispositions to biological dimensions: a narrative review on the synergy between oral health and vitamin D through the lens of Indian habitus.Frontiers in oral health · 2025Review
- The necessity of gestational vitamin D supplementation depends on ambient temperature: concern for infant vitamin D status.Frontiers in nutrition · 2025Article
- Association between Vitamin D and Dental Caries in a Sample of Canadian and American Preschool-Aged Children.Nutrients · 2021Article
- Association of parental-reported vitamin D supplementation with dental caries of 3-year-old children in Poland: a cross-sectional study.Clinical oral investigations · 2021Article
- Serum Levels of Vitamin D and Dental Caries in 7-Year-Old Children in Porto Metropolitan Area.Nutrients · 2021Article
- The antibacterial effects of vitamin D3 against mutans streptococci: an in vitro study.European oral research · 2021Article
- Vitamin D Deficiency and Oral Health: A Comprehensive Review.Nutrients · 2020Review
- A Review of the Potential Benefits of Increasing Vitamin D Status in Mongolian Adults through Food Fortification and Vitamin D Supplementation.Nutrients · 2019Review
- Vitamin DInternational journal of endocrinology · 2019Article
- Presence of Dental Caries Is Associated with Food Insecurity and Frequency of Breakfast Consumption in Korean Children and Adolescents.Preventive nutrition and food science · 2018Article
- Combined deficiencies of 25-hydroxyvitamin D and anemia in preschool children with severe early childhood caries: A case-control study.Paediatrics & child health · 2018Article
- Dental caries and vitamin D3 in children with growth hormone deficiency: A STROBE compliant study.Medicine · 2018Observational
- Vitamin D Compounds Are Bactericidal against Streptococcus mutans and Target the Bacitracin-Associated Efflux System.Antimicrobial agents and chemotherapy · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large geographical variations in dental health and tooth loss among US adolescents and young adults have been reported since the mid-1800s. Studies in the 1920s and 1930s noted that vitamin D and ultraviolet-B (UVB) irradiance reduced caries formation, the proposed mechanism being improved calcium absorption and metabolism. This paper reviews the history of studies of dental caries with respect to vitamin D, geographical location and available solar UVB doses. In addition, data on mean dental health rank by state for US servicemen from three periods, 1918, 1934 and 1943, were used in regression analyses with respect to summertime solar UVB doses and an index for mottled enamel, a proxy for natural fluoridation of drinking water, for 1935. There was a significant inverse correlation for dental health rank with respect to solar UVB from doses of 4.0 to 6.5 kJ/m(2) with little change thereafter. Adding data for mottled enamel rates for the states with UvB doses <6.6 kJ/m(2) improved the adjusted R(2) from 0.45 to 0.52. The mechanism whereby UVB reduces risk of dental caries is likely through production of vitamin D, followed by induction of cathelicidin and defensins, which have antimicrobial properties. Serum 25-hydroxyvitamin D concentrations at or above 30-40 ng/ml should significantly reduce the formation of dental caries. It is unfortunate that the UVB and vitamin D findings were not given more consideration in the 1950s as a way to reduce the risk of dental caries when water fluoridation was being proposed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.