Evidence map›Paper›PMID 22110613›Full record

SynthesisPloS one2011

Depression screening and patient outcomes in cancer: a systematic review.

Anna Meijer, Michelle Roseman, Katherine Milette, James C Coyne, Michael E Stefanek, Roy C Ziegelstein, Erin Arthurs, Allison Leavens, Steven C Palmer, Donna E Stewart and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Review
  6. Review
  7. Article
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  11. Article
  12. Confirmatory Factor Analysis of the Center for Epidemiologic Studies Depression Scale in Oncology With Examination of Invariance Between Younger and Older Patients.European journal of psychological assessment : official organ of the European Association of Psychological Assessment · 2020
    Article
  13. Symptom screening for constipation in oncology: getting to the bottom of the matter.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Article
  14. Observational
  15. Review
  16. Article
  17. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Anna MeijerInterdisciplinary Center for Psychiatric Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Michelle Roseman
Katherine Milette
James C Coyne
Michael E Stefanek
Roy C Ziegelstein
Erin Arthurs
Allison Leavens
Steven C Palmer
Donna E Stewart
Peter de Jonge
Brett D Thombs
Jewish General Hospital · CAUniversity of Groningen · NLIndiana University Bloomington · USJohns Hopkins Medicine · USMcGill University · CAUniversity Medical Center Groningen · NLUniversity of Pennsylvania · USUniversity of Toronto · CA

Funding

Canadian Institutes of Health Research 108456Canadian Institutes of Health Research SKI 83345
6 · The paper itself

Abstract

backgroundSeveral practice guidelines recommend screening for depression in cancer care, but no systematic reviews have examined whether there is evidence that depression screening benefits cancer patients. The objective was to evaluate the potential benefits of depression screening in cancer patients by assessing the (1) accuracy of depression screening tools; (2) effectiveness of depression treatment; and (3) effect of depression screening, either alone or in the context of comprehensive depression care, on depression outcomes.

methodsData sources were CINAHL, Cochrane, EMBASE, ISI, MEDLINE, PsycINFO and SCOPUS databases through January 24, 2011; manual journal searches; reference lists; citation tracking; trial registry reviews. Articles on cancer patients were included if they (1) compared a depression screening instrument to a valid criterion for major depressive disorder (MDD); (2) compared depression treatment with placebo or usual care in a randomized controlled trial (RCT); (3) assessed the effect of screening on depression outcomes in a RCT.

resultsThere were 19 studies of screening accuracy, 1 MDD treatment RCT, but no RCTs that investigated effects of screening on depression outcomes. Screening accuracy studies generally had small sample sizes (median = 17 depression cases) and used exploratory methods to set sample-specific cutoff scores that varied substantially across studies. A nurse-delivered intervention for MDD reduced depressive symptoms moderately (effect size = 0.37).

conclusionsThe one treatment study reviewed reported modest improvement in depressive symptoms, but no evidence was found on whether or not depression screening in cancer patients, either alone or in the context of optimal depression care, improves depression outcomes compared to usual care. Depression screening in cancer should be evaluated in a RCT in which all patients identified as depressed, either through screening or via physician recognition and referral in a control group, have access to comprehensive depression care.

Indexed as

HumansMajor Depressive DisorderNeoplasmsPrognosisSensitivity and Specificity

Identifiers

PMID22110613
PMCPMC3215716
OpenAlexW1983117185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.