Evidence map›Paper›PMID 22110610›Full record

ArticlePloS one2011

Effectiveness and limitations of hand hygiene promotion on decreasing healthcare-associated infections.

Yee-Chun Chen, Wang-Huei Sheng, Jann-Tay Wang, Shan-Chwen Chang, Hui-Chi Lin, Kuei-Lien Tien, Le-Yin Hsu, Keh-Sung Tsai

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07280026 (Effectiveness of an Edge AI-based Augmented Reality System for Hand Hygiene Training), which is not on this map. Cited by 45 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 6 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07280026 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of an Edge AI-based Augmented Reality System for Hand Hygiene Training: a Multi-centre, Mixed-methods Cluster Randomised Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2025 to 2027Enrolled1,000ConditionsHand Hygiene Training, Infection Prevention and Control, Healthcare-Associated Infections (HAIs), Health EducationArmsInstructional Video + Scanner Feedback, Edge AI-based AR Hand Hygiene Training System
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Interventions to improve hand hygiene compliance in patient care.The Cochrane database of systematic reviews · 2017
    Pooled it
  5. Pooled it
  6. Guideline
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Predictors of Compliance to Hand Hygiene among Health Care Workers in Rwanda.Rwanda journal of medicine and health sciences · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yee-Chun ChenCenter for Infection Control, National Taiwan University Hospital, Taipei, Taiwan. yeechunchen@gmail.com
Wang-Huei Sheng
Jann-Tay Wang
Shan-Chwen Chang
Hui-Chi Lin
Kuei-Lien Tien
Le-Yin Hsu
Keh-Sung Tsai
National Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited data describe the sustained impact of hand hygiene programs (HHPs) implemented in teaching hospitals, where the burden of healthcare-associated infections (HAIs) is high. We use a quasi-experimental, before and after, study design with prospective hospital-wide surveillance of HAIs to assess the cost effectiveness of HHPs. METHODS AND

findingsA 4-year hospital-wide HHP, with particular emphasis on using an alcohol-based hand rub, was implemented in April 2004 at a 2,200-bed teaching hospital in Taiwan. Compliance was measured by direct observation and the use of hand rub products. Poisson regression analyses were employed to evaluate the densities and trends of HAIs during the preintervention (January 1999 to March 2004) and intervention (April 2004 to December 2007) periods. The economic impact was estimated based on a case-control study in Taiwan. We observed 8,420 opportunities for hand hygiene during the study period. Compliance improved from 43.3% in April 2004 to 95.6% in 2007 (p<.001), and was closely correlated with increased consumption of the alcohol-based hand rub (r = 0.9399). The disease severity score (Charlson comorbidity index) increased (p = .002) during the intervention period. Nevertheless, we observed an 8.9% decrease in HAIs and a decline in the occurrence of bloodstream, methicillin-resistant Staphylococcus aureus, extensively drug-resistant Acinetobacter baumannii, and intensive care unit infections. The intervention had no discernable impact on HAI rates in the hematology/oncology wards. The net benefit of the HHP was US$5,289,364, and the benefit-cost ratio was 23.7 with a 3% discount rate.

conclusionsImplementation of a HHP reduces preventable HAIs and is cost effective.

Indexed as

Anti-Infective Agents, LocalBacterial InfectionsFemaleGuideline AdherenceHandHealth PersonnelHumansInfection ControlMaleMiddle AgedProspective StudiesAnti-Infective Agents, Local

Identifiers

PMID22110610
PMCPMC3217962
OpenAlexW2008918611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.