ReviewClinical & developmental immunology2012
Immunogenetic factors associated with severe respiratory illness caused by zoonotic H1N1 and H5N1 influenza viruses.
Review in Clinical & developmental immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Maternal Influenza and Offspring Neurodevelopment.Current issues in molecular biology · 2024Review
- Review
- OMIP-046: Characterization of invariant T cell subset activation in humans.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018Article
- Systems biology: A tool for charting the antiviral landscape.Virus research · 2016Review
- Avian Influenza A(H5N1) Virus in Egypt.Emerging infectious diseases · 2016Article
- Differences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Avian influenza A(H5N1) and A(H9N2) seroprevalence and risk factors for infection among Egyptians: a prospective, controlled seroepidemiological study.The Journal of infectious diseases · 2015Article
- Influenza, immune system, and pregnancy.Reproductive sciences (Thousand Oaks, Calif.) · 2014Review
- Article
- Heterogeneous pathological outcomes after experimental pH1N1 influenza infection in ferrets correlate with viral replication and host immune responses in the lung.Veterinary research · 2014Article
- Combining magnetic nanoparticle with biotinylated nanobodies for rapid and sensitive detection of influenza H3N2.Nanoscale research letters · 2014Article
- Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique.PloS one · 2013Article
- Immunopathogenesis of 2009 pandemic influenza.Enfermedades infecciosas y microbiologia clinica · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following the 2009 H1N1 pandemic and ongoing sporadic avian-to-human transmission of H5N1 viruses, an emphasis has been placed on better understanding the determinants and pathogenesis of severe influenza infections. Much of the current literature has focused on viral genetics and its impact on host immunity as well as novel risk factors for severe infection (particularly within the H1N1 pandemic). An understanding of the host genetic determinants of susceptibility and severe respiratory illness, however, is currently lacking. By better defining the role of genetic variability in influenza infection and identifying key polymorphisms that impair the host immune response or correlate with protection, we will be able to better identify at-risk populations and new targets for therapeutic interventions and vaccines. This paper will summarize known immunogenetic factors associated with susceptibility or severity of both pH1N1 and H5N1 infections and will also identify genetic pathways and polymorphisms of high relevance for future study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.