Evidence map›Paper›PMID 22110527›Full record

ArticleClinical & developmental immunology2011

Molecular and immunological characterization of Staphylococcus aureus in pediatric atopic dermatitis: implications for prophylaxis and clinical management.

Chiara Pascolini, Jolinda Sinagra, Simone Pecetta, Valentina Bordignon, Alessandra De Santis, Laura Cilli, Viviana Cafiso, Grazia Prignano, Bruno Capitanio, Claudio Passariello and 3 more

Open access · goldAbstract read
In one paragraph

Article in Clinical & developmental immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. UltrastrongScience advances · 2025
    Article
  2. Review
  3. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Investigating genomic diversity ofFrontiers in microbiology · 2024
    Article
  5. Article
  6. Atopic dermatitis-derivedFrontiers in cellular and infection microbiology · 2023
    Article
  7. Article
  8. Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis.JID innovations : skin science from molecules to population health · 2022
    Review
  9. Article
  10. Methicillin-resistantVirulence · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Colonization WithFrontiers in microbiology · 2020
    Review
  15. Microorganisms · 2019
    Review
  16. Article
  17. Article
  18. Article
  19. Staphylococcus aureus colonization related to severity of hand eczema.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Article
  20. The role of the skin microbiome in atopic dermatitis.Current allergy and asthma reports · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chiara PascoliniClinical Pathology and Microbiology Laboratory and Pediatric Dermatology Division, San Gallicano Dermatology Institute, 00144 Rome, Italy.
Jolinda Sinagra
Simone Pecetta
Valentina Bordignon
Alessandra De Santis
Laura Cilli
Viviana Cafiso
Grazia Prignano
Bruno Capitanio
Claudio Passariello
Stefania Stefani
Paola Cordiali-Fei
Fabrizio Ensoli
San Gallicano Hospital · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

S. aureus represents a critical cofactor in atopic dermatitis (AD). In this paper, the prevalence of S. aureus infection/colonization was evaluated in 117 children as well as in their cohabitants, in order to assess the value of S. aureus characterization in predicting disease onset and severity and in providing indications for prophylaxis. Results showed that children with AD as well as their cohabitants had a significantly greater incidence of S. aureus infection/colonization as compared to controls. The genetic characterization showed a virtual identity of the bacteria strains collected at different sites of the patients with those found in the cohabitants, suggesting both a direct transmission between the nasal reservoir and the lesions in the same atopic subject and a risk for reinfection within family cohabitants. These data stress the need of preliminary laboratory assessment and posttherapy control in both AD patients and their close contacts for effective S. aureus eradication.

Indexed as

ChildChild, PreschoolDermatitis, AtopicDisease Transmission, InfectiousDNA, BacterialFamilyFemaleFollow-Up StudiesHumansIncidenceMalePrevalencePrognosisStaphylococcal InfectionsStaphylococcus aureusDNA, Bacterial

Identifiers

PMID22110527
PMCPMC3205653
OpenAlexW2158209861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.