Evidence map›Paper›PMID 22110392›Full record

ReviewInternational journal of biological sciences2011

Mechanisms underlying the induction of regulatory T cells and its relevance in the adaptive immune response in parasitic infections.

Laura Adalid-Peralta, Gladis Fragoso, Agnes Fleury, Edda Sciutto

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Immune modulation of Th1/Th2/Treg/Th17/Th9/Th21 cells in rabbits infected withFrontiers in cellular and infection microbiology · 2023
    Article
  6. Article
  7. Article
  8. Immunosuppression in Malaria: DoPathogens (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Immunogenicity Challenges Associated with Subcutaneous Delivery of Therapeutic Proteins.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2021
    Review
  11. Article
  12. A Nutritional Supplement (DìLshAnimals : an open access journal from MDPI · 2020
    Article
  13. Article
  14. Review
  15. Article
  16. Recombinant protein ofOncotarget · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Laura Adalid-PeraltaInstituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, México.
Gladis Fragoso
Agnes Fleury
Edda Sciutto
Instituto Nacional de Investigaciones Nucleares · MXInstituto Nacional de Neurología y Neurocirugía · MXUniversidad Insurgentes · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To fulfill its function, the immune system must detect and interpret a wide variety of signals and adjust the magnitude, duration, and specific traits of each response during the complex host-parasite relationships in parasitic infections. Inflammation must be tightly regulated since uncontrolled inflammation may be as destructive as the triggering stimulus and leads to immune-mediated tissue injury. During recent years, increasing evidence points to regulatory T cells (Tregs) as key anti-inflammatory cells, critically involved in limiting the inflammatory response. Herein, we review the published information on the induction of Tregs and summarize the most recent findings on Treg generation in parasitic diseases.

Indexed as

Adaptive ImmunityCytokinesDendritic CellsHumansMalariaProtozoan InfectionsT-Lymphocytes, RegulatoryCytokinescytokinesdendritic cellimmune responseinflammationLeishmaniamalarianematodes.parasitic infectionsregulationregulatory T cellsSchistosomaTrypanosoma

Identifiers

PMID22110392
PMCPMC3221948
OpenAlexW2170143887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.