Evidence map›Paper›PMID 22110158›Full record

Trial reportAmerican journal of Alzheimer's disease and other dementias2011

A novel technology to screen for cognitive impairment in the elderly.

David W Wright, Harriet Nevárez, Patrick Kilgo, Michelle LaPlaca, Amber Robinson, Shawn Fowler, John Brumfield, Felicia C Goldstein

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in American journal of Alzheimer's disease and other dementias, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00454454 (Display Enhanced TEsting for Cognitive Impairment and Traumatic Brain Injury), which is not on this map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00454454 completednot on this map

Display Enhanced TEsting for Cognitive Impairment and Traumatic Brain Injury

TypeobservationalSponsorEmory UniversityRan2007 to 2010Enrolled425ConditionsMemory
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Mini-Cog for the detection of dementia within a secondary care setting.The Cochrane database of systematic reviews · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David W WrightEmory University School of Medicine, Department of Emergency Medicine, Atlanta, GA 30303, USA. david.wright@emory.edu
Harriet Nevárez
Patrick Kilgo
Michelle LaPlaca
Amber Robinson
Shawn Fowler
John Brumfield
Felicia C Goldstein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional evaluation of mild cognitive impairment (MCI) can be costly, time consuming, and impractical for widespread screening. DETECT is a portable device developed to rapidly perform cognitive testing in diverse settings. This study compares DETECT with formal clinical assessment.

methodsA prospective cross-sectional comparison of the DETECT device versus an expert neuropsychologist's assessment (NPA). A total of 405 participants ≥65 years old, recruited from geriatric clinics and retirement facilities, completed both DETECT and NPA. Multivariable logistic regression methods were used to evaluate the degree of correlation between DETECT testing and the NPA diagnosis.

resultsPredictive modeling demonstrated very good ability to discriminate between normal, MCI, and dementia per the NPA reference standard using DETECT subtests (c = 0.85 for any impairment; c = 0.99 for dementia).

conclusionDETECT scores closely correlate with NPA. DETECT can identify and discriminate between normal, MCI, and dementia and could be incorporated as a screener for MCI.

Indexed as

Neuropsychological TestsAgedAlzheimer DiseaseAttentionCognition DisordersCross-Sectional StudiesDiagnosis, Computer-AssistedDiagnosis, DifferentialEarly DiagnosisExecutive FunctionHumansLogistic ModelsMass ScreeningMemoryMultivariate AnalysisPredictive Value of Tests

Identifiers

PMID22110158
PMCPMC10845310

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.