Trial reportEuropean journal of nuclear medicine and molecular imaging2012
Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: a prospective, multicentre trial.
Trial report in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Long-term prognostic value of stress myocardial perfusion imaging and coronary computed tomography angiography: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Pooled it
- Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Pooled it
- Comparative effectiveness of positron emission tomography and single-photon emission computed tomography myocardial perfusion imaging for predicting risk in patients with cardiometabolic disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2024Article
- A machine learning-based approach to directly compare the diagnostic accuracy of myocardial perfusion imaging by conventional and cadmium-zinc telluride SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Myocardial perfusion imaging for diabetes: Key points from the evidence and clinical questions to be answered.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Automated Inline Analysis of Myocardial Perfusion MRI with Deep Learning.Radiology. Artificial intelligence · 2020Article
- Added prognostic value of left ventricular shape by gated SPECT imaging in patients with suspected coronary artery disease and normal myocardial perfusion.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Cardiovascular Screening for the Asymptomatic Patient with Diabetes: More Cons Than Pros.Journal of diabetes research · 2017Review
- Serial cardiac SPECT studies: Technical issues and clinical implications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Prognostication in the era of a new stressor for myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Screening asymptomatic patients with type 2 diabetes is recommended: Pro.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Screening asymptomatic patients with type 2 diabetes: The debates persist.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Prevalence and Severity of Myocardial Perfusion Imaging Abnormalities in Inmate Subjects.PloS one · 2015Article
- Cardiovascular risk stratification in diabetic patients: is all in METS?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Warranty period of normal stress myocardial perfusion imaging in diabetic patients: a propensity score analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Detection of silent myocardial ischemia: is it clinically relevant?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Prevalence and predictors of ischemia and outcomes in outpatients with diabetes mellitus referred for single-photon emission computed tomography myocardial perfusion imaging.Circulation. Cardiovascular imaging · 2013Article
- Microalbuminuria predicts silent myocardial ischaemia in type 2 diabetes patients.European journal of nuclear medicine and molecular imaging · 2013Article
- Metabolic syndrome is not a predictor for cardiovascular events in Japanese patients with diabetes mellitus asymptomatic for coronary artery disease: a retrospective analysis of the J-ACCESS-2 study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine whether stress-rest myocardial perfusion single-photon emission (MPS) computed tomography improves coronary heart disease (CHD) risk classification in diabetic patients.
methodsIn 822 consecutive diabetic patients, risk estimates for a CHD event were categorized as 0% to <3%, 3% to <5%, and ≥5% per year using Cox proportional hazards models. Model 1 used traditional CHD risk factors and electrocardiography (ECG) stress test data and model 2 used these variables plus MPS imaging data. We calculated the net reclassification improvement (NRI) and compared the distribution of risk using model 2 vs. model 1. CHD death, myocardial infarction and unstable angina requiring coronary revascularization were the outcome measures.
resultsDuring follow-up (58 ± 11 months), 148 events occurred. Model 2 improved risk prediction compared to model 1 (NRI 0.25, 95% confidence interval, CI, 0.15-0.34; p < 0.001). Overall, 301 patients were reclassified to a higher risk category, with an event rate of 28%, and 26 to a lower risk category, with an event rate of 15%. Among patients at 3% to <5% risk, 53% were reclassified at higher risk and 25% at lower risk (NRI 0.42, 95% CI 0.07-0.76; p < 0.05). The cost per NRI was $880.80 for MPS imaging as compared to an outpatient visit with an ECG stress test.
conclusionThe addition of MPS imaging data to a prediction model based on traditional risk factors and ECG stress test data significantly improved CHD risk classification in patients with diabetes.
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