ArticleProceedings of the National Academy of Sciences of the United States of America2011
Interaction of cellular and network mechanisms for efficient pheromone coding in moths.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Stimulus duration encoding occurs early in the moth olfactory pathway.Communications biology · 2024Article
- Olfactory navigation in arthropods.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Review
- Experimental and theoretical probe on mechano- and chemosensory integration in the insect antennal lobe.Frontiers in physiology · 2022Article
- Effects of Mechanosensory Input on the Tracking of Pulsatile Odor Stimuli by Moth Antennal Lobe Neurons.Frontiers in neuroscience · 2021Article
- Neuronal Response Latencies Encode First Odor Identity Information across Subjects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Intrinsic and Network Mechanisms Constrain Neural Synchrony in the Moth Antennal Lobe.Frontiers in physiology · 2016Article
- Modeling the cellular mechanisms and olfactory input underlying the triphasic response of moth pheromone-sensitive projection neurons.PloS one · 2015Article
- Computational models to understand decision making and pattern recognition in the insect brain.Current opinion in insect science · 2014Article
- Heterogeneity and convergence of olfactory first-order neurons account for the high speed and sensitivity of second-order neurons.PLoS computational biology · 2014Article
- Rapid and slow chemical synaptic interactions of cholinergic projection neurons and GABAergic local interneurons in the insect antennal lobe.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Temporal features of spike trains in the moth antennal lobe revealed by a comparative time-frequency analysis.PloS one · 2014Article
- Parallel processing via a dual olfactory pathway in the honeybee.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Peripheral coding of sex pheromone blends with reverse ratios in two helicoverpa species.PloS one · 2013Article
- Multiphasic on/off pheromone signalling in moths as neural correlates of a search strategy.PloS one · 2013Article
- Gain control network conditions in early sensory coding.PLoS computational biology · 2013Article
- Keeping their distance? Odor response patterns along the concentration range.Frontiers in systems neuroscience · 2012Article
- Glomerular latency coding in artificial olfaction.Frontiers in neuroengineering · 2011Article
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4 authors.
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Abstract
Sensory systems, both in the living and in machines, have to be optimized with respect to their environmental conditions. The pheromone subsystem of the olfactory system of moths is a particularly well-defined example in which rapid variations of odor content in turbulent plumes require fast, concentration-invariant neural representations. It is not clear how cellular and network mechanisms in the moth antennal lobe contribute to coding efficiency. Using computational modeling, we show that intrinsic potassium currents (I(A) and I(SK)) in projection neurons may combine with extrinsic inhibition from local interneurons to implement a dual latency code for both pheromone identity and intensity. The mean latency reflects stimulus intensity, whereas latency differences carry concentration-invariant information about stimulus identity. In accordance with physiological results, the projection neurons exhibit a multiphasic response of inhibition-excitation-inhibition. Together with synaptic inhibition, intrinsic currents I(A) and I(SK) account for the first and second inhibitory phases and contribute to a rapid encoding of pheromone information. The first inhibition plays the role of a reset to limit variability in the time to first spike. The second inhibition prevents responses of excessive duration to allow tracking of intermittent stimuli.
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