ReviewHeredity2012
Molecular cytogenetic and genomic insights into chromosomal evolution.
Review in Heredity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 65 citations in OpenAlex.
- Divergent 3D genome architecture of male germ cells across vertebrates.Nature communications · 2026Article
- Genomic comparisons and the adaptive basis of brain size plasticity and chromosomal instability in the Eurasian common shrew.Molecular biology and evolution · 2026Article
- Evolution of chromosomes and nuclear architectures of amniotes.Nature communications · 2025Article
- Chromosome-level echidna genome illuminates evolution of multiple sex chromosome system in monotremes.GigaScience · 2025Article
- Karyological analysis ofZooKeys · 2025Article
- De novo genome assemblies of two cryptodiran turtles with ZZ/ZW and XX/XY sex chromosomes provide insights into patterns of genome reshuffling and uncover novel 3D genome folding in amniotes.Genome research · 2024Article
- Karyotypes of water frogs from the Pelophylax esculentus complex: results of cross-species chromosomal painting.Chromosoma · 2023Article
- Evolution of the ancestral mammalian karyotype and syntenic regions.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Strategies for meiotic sex chromosome dynamics and telomeric elongation in Marsupials.PLoS genetics · 2022Article
- Meiotic chromosome dynamics and double strand break formation in reptiles.Frontiers in cell and developmental biology · 2022Article
- Sex chromosome evolution among amniotes: is the origin of sex chromosomes non-random?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
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- The Plasticity of Genome Architecture.Genes · 2020Article
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- Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes.Genome biology · 2018Article
- Comparative analysis of palmitoylation sites of serotonin (5-HT) receptors in vertebrates.Neuropsychopharmacology reports · 2018Article
- Reconstruction and evolutionary history of eutherian chromosomes.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- The impact of the protein interactome on the syntenic structure of mammalian genomes.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes aspects of the extensive literature on the patterns and processes underpinning chromosomal evolution in vertebrates and especially placental mammals. It highlights the growing synergy between molecular cytogenetics and comparative genomics, particularly with respect to fully or partially sequenced genomes, and provides novel insights into changes in chromosome number and structure across deep division of the vertebrate tree of life. The examination of basal numbers in the deeper branches of the vertebrate tree suggest a haploid (n) chromosome number of 10-13 in an ancestral vertebrate, with modest increases in tetrapods and amniotes most probably by chromosomal fissioning. Information drawn largely from cross-species chromosome painting in the data-dense Placentalia permits the confident reconstruction of an ancestral karyotype comprising n=23 chromosomes that is similarly retained in Boreoeutheria. Using in silico genome-wide scans that include the newly released frog genome we show that of the nine ancient syntenies detected in conserved karyotypes of extant placentals (thought likely to reflect the structure of ancestral chromosomes), the human syntenic segmental associations 3p/21, 4pq/8p, 7a/16p, 14/15, 12qt/22q and 12pq/22qt predate the divergence of tetrapods. These findings underscore the enhanced quality of ancestral reconstructions based on the integrative molecular cytogenetic and comparative genomic approaches that collectively highlight a pattern of conserved syntenic associations that extends back ∼360 million years ago.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.