Evidence map›Paper›PMID 22108139›Full record

ReviewJournal of neuroscience methods2012

A review of multivariate methods for multimodal fusion of brain imaging data.

Jing Sui, Tülay Adali, Qingbao Yu, Jiayu Chen, Vince D Calhoun

Abstract readComparative StudyReview
In one paragraph

Review in Journal of neuroscience methods, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 179 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing SuiThe Mind Research Network, Albuquerque, NM 87106, USA. Electronic address: jsui@mrn.org.
Tülay AdaliDept. of CSEE, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.
Qingbao YuThe Mind Research Network, Albuquerque, NM 87106, USA.
Jiayu ChenThe Mind Research Network, Albuquerque, NM 87106, USA; Dept. of ECE, University of New Mexico, Albuquerque, NM 87131, USA.
Vince D CalhounThe Mind Research Network, Albuquerque, NM 87106, USA; Dept. of ECE, University of New Mexico, Albuquerque, NM 87131, USA; Dept. of Psychiatry, Yale University, New Haven, CT 06519, USA.

Funding

Multivariate methods for identifying multitask/multimodal brain imaging biomarkersR01EB006841 · NIBIB · THE MIND RESEARCH NETWORK · PI VINCE D CALHOUN, Sergey Plis · 2007 to 2026
$9.8M
Informed Data-Driven Fusion of Behavior, Brain Function, and GenesR01EB005846 · NIBIB · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D · 2005 to 2016
$5.5M
Unified multivariate data-driven solutions for static and dynamic brain connectivityR01EB020407 · NIBIB · THE MIND RESEARCH NETWORK · PI ADALI, TULAY, CALHOUN, VINCE D · 2015 to 2018
$2.7M
NIBIB NIH HHS R01 EB005846NIBIB NIH HHS R01EB 005846NIBIB NIH HHS R01 EB006841NIBIB NIH HHS R01EB 006841NIBIB NIH HHS R01 EB020407
6 · The paper itself

Abstract

The development of various neuroimaging techniques is rapidly improving the measurements of brain function/structure. However, despite improvements in individual modalities, it is becoming increasingly clear that the most effective research approaches will utilize multi-modal fusion, which takes advantage of the fact that each modality provides a limited view of the brain. The goal of multi-modal fusion is to capitalize on the strength of each modality in a joint analysis, rather than a separate analysis of each. This is a more complicated endeavor that must be approached more carefully and efficient methods should be developed to draw generalized and valid conclusions from high dimensional data with a limited number of subjects. Numerous research efforts have been reported in the field based on various statistical approaches, e.g. independent component analysis (ICA), canonical correlation analysis (CCA) and partial least squares (PLS). In this review paper, we survey a number of multivariate methods appearing in previous multimodal fusion reports, mostly fMRI with other modality, which were performed with or without prior information. A table for comparing optimization assumptions, purpose of the analysis, the need of priors, dimension reduction strategies and input data types is provided, which may serve as a valuable reference that helps readers understand the trade-offs of the 7 methods comprehensively. Finally, we evaluate 3 representative methods via simulation and give some suggestions on how to select an appropriate method based on a given research.

Indexed as

Multivariate AnalysisSubtraction TechniqueAnimalsBrainData Interpretation, StatisticalFunctional NeuroimagingHumansImage Interpretation, Computer-AssistedPattern Recognition, AutomatedReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID22108139
PMCPMC3690333

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.