ArticleProceedings of the National Academy of Sciences of the United States of America2011
Organelle-nucleus cross-talk regulates plant intercellular communication via plasmodesmata.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 105 citations in OpenAlex.
- Glucose-TOR-PDCB signaling restricts cell-to-cell communication through callose deposition.Science advances · 2026Article
- Interspecific secondary plasmodesmata at the parasitic interface.Plant & cell physiology · 2026Review
- Cell-to-cell connectivity: a future target for crop improvement.Journal of experimental botany · 2026Review
- Defence-mediated phloem restriction of a plant virus facilitates insect transmission.Nature communications · 2025Article
- Xyloglucan Endotransglycosylase/Hydrolase Downregulation IncreasesInternational journal of molecular sciences · 2025Article
- Article
- Glucosinolates can act as signals to modulate intercellular trafficking via plasmodesmata.The New phytologist · 2025Article
- New insights into plasmodesmata: complex 'protoplasmic connecting threads'.Journal of experimental botany · 2024Review
- Reversible S-nitrosylation of bZIP67 by peroxiredoxin IIE activity and nitro-fatty acids regulates the plant lipid profile.Cell reports · 2024Article
- The dicot homolog of maize PPR103 carries a C-terminal DYW domain and may have a role in C-to-U editing of some chloroplast RNA transcripts.Plant molecular biology · 2024Article
- Distributing Plant Developmental Regulatory Proteins via Plasmodesmata.Plants (Basel, Switzerland) · 2024Review
- Communicating Across Cell Walls: Structure, Evolution, and Regulation of Plasmodesmatal Transport in Plants.Results and problems in cell differentiation · 2024Review
- Plasmodesmal connectivity in CThe New phytologist · 2024Article
- Metabolic regulation of quiescence in plants.The Plant journal : for cell and molecular biology · 2023Article
- A novel cellular factor ofFrontiers in plant science · 2023Article
- Article
- Enzymatic fingerprinting reveals specific xyloglucan and pectin signatures in the cell wall purified with primary plasmodesmata.Frontiers in plant science · 2022Article
- Quantifying Plasmodesmatal Transport with an Improved GFP Movement Assay.Methods in molecular biology (Clifton, N.J.) · 2022Article
- TOR coordinates nucleotide availability with ribosome biogenesis in plants.The Plant cell · 2021Article
- Cytokinins Stimulate Plasmodesmatal Transport in Leaves.Frontiers in plant science · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
We use Arabidopsis thaliana embryogenesis as a model system for studying intercellular transport via plasmodesmata (PD). A forward genetic screen for altered PD transport identified increased size exclusion limit (ise) 1 and ise2 mutants with increased intercellular transport of fluorescent 10-kDa tracers. Both ise1 and ise2 exhibit increased formation of twinned and branched PD. ISE1 encodes a mitochondrial DEAD-box RNA helicase, whereas ISE2 encodes a DEVH-type RNA helicase. Here, we show that ISE2 foci are localized to the chloroplast stroma. Surprisingly, plastid development is defective in both ise1 and ise2 mutant embryos. In an effort to understand how RNA helicases that localize to different organelles have similar impacts on plastid and PD development/function, we performed whole-genome expression analyses. The most significantly affected class of transcripts in both mutants encode products that target to and enable plastid function. These results reinforce the importance of plastid-mitochondria-nucleus cross-talk, add PD as a critical player in the plant cell communication network, and thereby illuminate a previously undescribed signaling pathway dubbed organelle-nucleus-plasmodesmata signaling. Several genes with roles in cell wall synthesis and modification are also differentially expressed in both mutants, providing new targets for investigating PD development and function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.