ArticleProceedings of the National Academy of Sciences of the United States of America2011
Brassinosteroid control of sex determination in maize.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
134 citing papers in PubMed, 1 synthesis or guideline pooled it, 264 citations in OpenAlex.
- Pooled it
- Integrative Hormone Metabolomic, Transcriptomic, and miRNA Sequencing Analyses Reveal Brassinosteroid-Mediated Sex Differentiation in Walnut Flower Buds.Plants (Basel, Switzerland) · 2026Article
- A multi-omics approach to maize (Zea mays) tassel development.BMC plant biology · 2026Article
- Article
- Genetic basis of pedicellate spikelet masculinization in maize revealed by an advanced maize-teosinte population.Planta · 2026Article
- Article
- Sexual Dimorphism on a Conserved Scaffold: Insights from the Floral Ontogeny ofPlants (Basel, Switzerland) · 2025Article
- Vitazyme biostimulant increases specialty crop production and contains active brassinosteroids; a spectrofluorometric, chemical (LCMS), and bioassay determination.BMC plant biology · 2025Article
- A maize mutant in the glutamate receptor-like dwarf13 is modified by cis-acting natural variation and a cornichon homolog.PLoS genetics · 2025Article
- Article
- A novel method for effectively selecting fragments not associated with restriction sites for whole-genome genotyping.BMC biology · 2025Article
- A multi-parent population approach to reveal the genetic basis of plant height in maize.BMC plant biology · 2025Article
- Genome-Wide Association Analysis of Fresh Maize.International journal of molecular sciences · 2025Article
- Brassinosteroids in Cucurbits: Modulators of Plant Growth Architecture and Stress Response.International journal of molecular sciences · 2025Review
- A BRASSINOSTEROID INSENSISTIVE 1 receptor kinase ortholog is required for sex determination in Ceratopteris richardii.The Plant cell · 2025Article
- Integrative mapping in large inbred and hybrid association panels along with an FTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genetic Diversity Analysis and GWAS of Plant Height and Ear Height in Maize Inbred Lines from South-East China.Plants (Basel, Switzerland) · 2025Article
- STay tunEd: mutational analysis of theFrontiers in plant science · 2025Article
- Hormonal influence on maize inflorescence development and reproduction.Plant reproduction · 2024Review
- Identification of male sterility-related genes in Saccharum officinarum and Saccharum spontaneum.Plant reproduction · 2024Article
74 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brassinosteroids (BRs) are plant hormones that regulate growth and development. They share structural similarities with animal steroids, which are decisive factors of sex determination. BRs are known to regulate morphogenesis and environmental stress responses, but their involvement in sex determination in plants has been only speculative. We show that BRs control sex determination in maize revealed through characterization of the classical dwarf mutant nana plant1 (na1), which also feminizes male flowers. na1 plants carry a loss-of-function mutation in a DET2 homolog--a gene in the BR biosynthetic pathway. The mutant accumulates the DET2-specific substrate (24R)-24-methylcholest-4-en-3-one with a concomitant decrease of downstream BR metabolites. Treatment of wild-type maize plants with BR biosynthesis inhibitors completely mimicked both dwarf and tasselseed phenotypes of na1 mutants. Tissue-specific na1 expression in anthers throughout their development supports the hypothesis that BRs promote masculinity of the male inflorescence. These findings suggest that, in the monoecious plant maize, BRs have been coopted to perform a sex determination function not found in plants with bisexual flowers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.