Evidence map›Paper›PMID 22105147›Full record

ReviewMedical oncology (Northwood, London, England)2012

Role of the recently identified dysadherin in E-cadherin adhesion molecule downregulation in head and neck cancer.

Alexandros Georgolios, Anna Eleftheriadou, Anna Batistatou, Kostandinos Charalabopoulos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The translatome of glioblastoma.Molecular oncology · 2025
    Article
  4. Article
  5. A single-cell survey of the human glomerulonephritis.Journal of cellular and molecular medicine · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Alexandros GeorgoliosDepartment of Otorhinolaryngology, Virginia Commonwealth University, Richmond, VA, USA.
Anna Eleftheriadou
Anna Batistatou
Kostandinos Charalabopoulos
Crete University Press · GRDemocritus University of Thrace · GRUniversity of Ioannina · GRVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysadherin is a cancer-related cell membrane glycoprotein, recently identified, playing an important role in tumor progression and metastasis. In the present minireview article, we are focusing on the role of dysadherin in E-cadherin downregulation, the various expression patterns of the molecule in head and neck cancer as well as its potential role as a molecular target for future applications in diagnosis, clinical routine and prognosis of the disease.

Indexed as

Biomarkers, TumorCadherinsDown-RegulationGene Expression Regulation, NeoplasticHead and Neck NeoplasmsHumansIon ChannelsMembrane GlycoproteinsMicrofilament ProteinsNeoplasm ProteinsBiomarkers, TumorCadherinsFXYD5 protein, humanIon ChannelsMembrane GlycoproteinsMicrofilament ProteinsNeoplasm Proteins

Identifiers

PMID22105147
OpenAlexW2081009628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.