ReviewNature reviews. Gastroenterology & hepatology2011
MRI in Crohn's disease--current and future clinical applications.
Review in Nature reviews. Gastroenterology & hepatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Challenge of Small Intestine Length Measurement: A Systematic Review of Imaging Techniques.The Journal of surgical research · 2023Pooled it
- Clinical utility of magnetic resonance enterography for pediatric Crohn's disease: a review with illustrative cases and a focus on Japan.Japanese journal of radiology · 2026Review
- Current practice and innovations in diagnosing perianal fistulizing Crohn's disease (pfCD): a narrative review.Techniques in coloproctology · 2025Review
- Assessment of intestinal luminal stenosis and prediction of endoscopy passage in Crohn's disease patients using MRI.Insights into imaging · 2024Article
- Endoscopy-based IBD identification by a quantized deep learning pipeline.BioData mining · 2023Article
- Assessment of Ileal Crohn's Disease Activity by Gastrointestinal Ultrasound and MR Enterography: A Pilot Study.Life (Basel, Switzerland) · 2023Article
- Changes in the Management of Patients with Crohn's Disease Based on Magnetic Resonance Enterography Patterns.Gastroenterology research and practice · 2019Article
- Detection of Small Bowel Mucosal Healing and Deep Remission in Patients With Known Small Bowel Crohn's Disease Using Biomarkers, Capsule Endoscopy, and Imaging.The American journal of gastroenterology · 2015Observational
- Differential diagnosis in inflammatory bowel disease colitis: state of the art and future perspectives.World journal of gastroenterology · 2015Review
- Intestinal stricture in Crohn's disease.Intestinal research · 2015Review
- Treatment of peri-anal fistula in Crohn's disease.World journal of gastroenterology · 2014Review
- IBD: Mucosal healing--EXTENDing our knowledge in Crohn's disease.Nature reviews. Gastroenterology & hepatology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crohn's disease is a chronic, disabling disease that, over time, can lead to irreversible bowel damage. MRI can be used to diagnose and assess the activity, severity and complications of Crohn's disease; however, the role of MRI in therapeutic monitoring of changes in disease-related intestinal damage is still to be defined. Objective, validated MRI-based scores have been developed to assess the activity of Crohn's disease; these indices are based on the extent and severity of intestinal inflammation, postoperative recurrence and perianal disease. MRI is accurate, safe, reproducible and can allow repeated evaluations of patients without radiation exposure. Evidence that MRI might be valuable in the therapeutic monitoring of patients with Crohn's disease is increasing and, in combination with endoscopy and surgical history, this imaging technique could enable clinicians to assess Crohn's-disease-related intestinal damage. MRI could, therefore, have a crucial role in a future 'damage-driven' treatment paradigm--in which imaging is used to monitor intestinal damage and medication use is targeted to prevent the accumulation of further damage. This damage-driven therapeutic approach could potentially change the course of Crohn's disease.
Indexed as
Identifiers
22105109What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.