ReviewTrends in neurosciences2012
Developmental neuroplasticity after cochlear implantation.
Review in Trends in neurosciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 245 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
245 citing papers in PubMed, 5 syntheses or guidelines pooled it, 635 citations in OpenAlex.
- Neurocognitive function in children with cochlear implants and hearing aids: a systematic review.Frontiers in neuroscience · 2023Pooled it
- Brain Morphological Modifications in Congenital and Acquired Auditory Deprivation: A Systematic Review and Coordinate-Based Meta-Analysis.Frontiers in neuroscience · 2022Pooled it
- Hearing loss impacts gray and white matter across the lifespan: Systematic review, meta-analysis and meta-regression.NeuroImage · 2021Pooled it
- The Impact of Early Deafness on Brain Plasticity: A Systematic Review of the White and Gray Matter Changes.Frontiers in neuroscience · 2020Pooled it
- The Cross-Modal Effects of Sensory Deprivation on Spatial and Temporal Processes in Vision and Audition: A Systematic Review on Behavioral and Neuroimaging Research since 2000.Neural plasticity · 2019Pooled it
- Deafness alters the spatial mapping of touch.PloS one · 2018Trial
- Trial
- Results of Postoperative, CT-based, Electrode Deactivation on Hearing in Prelingually Deafened Adult Cochlear Implant Recipients.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2016Trial
- Longitudinal adaptations in neural and behavioral systems following hearing restoration using cochlear implants.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Rehabilitation Strategies for Pediatric Single-Sided Deafness, Including Children with Asymmetric Hearing Loss: A Systematic Review.Audiology research · 2026Review
- Speech sensorimotor adaptation in young adult cochlear implant users with early implantation.Journal of neurophysiology · 2026Article
- Age-Dependent Auditory Plasticity: Critical Periods in Subcortical and Cortical Encoding.Journal of audiology & otology · 2026Review
- Language Learning Activities in Educational Settings Incrementally Predict Language Ability Beyond Daily Conversation in Preschoolers with Cochlear Implants: A Comparative Study with Normal-Hearing Peers.Children (Basel, Switzerland) · 2026Article
- Impacts of hearing history, etiology, vestibular and balance function, and socioeconomic marginalization on developmental outcomes in children with cochlear implants.Scientific reports · 2026Article
- Developmental trajectories of somatostatin-positive interneurons in the human auditory cortex from migration to maturation.Communications biology · 2026Article
- Nonword Repetition Assessing Auditory and Cognitive Abilities in Adult Cochlear Implant Users.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Auditory-Somatosensory Interactions in Speech Perception in Individuals With Hearing Impairment: An Exploratory Case Study.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Home Language Activities and Language Ability Between Chinese Preschool Children with Cochlear Implants and Children with Normal Hearing.Audiology research · 2026Article
- Multi-Level Perception Systems in Fusion of Lifeforms: Classification, Challenges and Future Conceptions.Sensors (Basel, Switzerland) · 2026Review
- Using cortical auditory-evoked potential responses to verify the objective benefit of aural rehabilitation in adult cochlear implant users.Frontiers in neuroscience · 2026Article
185 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Cortical development is dependent on stimulus-driven learning. The absence of sensory input from birth, as occurs in congenital deafness, affects normal growth and connectivity needed to form a functional sensory system, resulting in deficits in oral language learning. Cochlear implants bypass cochlear damage by directly stimulating the auditory nerve and brain, making it possible to avoid many of the deleterious effects of sensory deprivation. Congenitally deaf animals and children who receive implants provide a platform to examine the characteristics of cortical plasticity in the auditory system. In this review, we discuss the existence of time limits for, and mechanistic constraints on, sensitive periods for cochlear implantation and describe the effects of multimodal and cognitive reorganization that result from long-term auditory deprivation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.