Trial reportActa orthopaedica2011
Metal ion levels and functional results after either resurfacing hip arthroplasty or conventional metal-on-metal hip arthroplasty.
Trial report in Acta orthopaedica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The Choice of Hip Arthroplasty: HRA or THA? Revealed by Meta-Analysis.Orthopaedic surgery · 2025Pooled it
- Choice of implant combinations in total hip replacement: systematic review and network meta-analysis.BMJ (Clinical research ed.) · 2017Pooled it
- Pooled it
- Hip resurfacing: a systematic review of literature.International orthopaedics · 2012Pooled it
- Trial
- Kinetics and Fluid-Specific Behavior of Metal Ions After Hip Replacement.Bioengineering (Basel, Switzerland) · 2025Article
- Patient reported outcomes during the first month following anterior and posterior total hip arthroplasty and hip resurfacing.BMC musculoskeletal disorders · 2025Article
- Prosthetic Metals: Release, Metabolism and Toxicity.International journal of nanomedicine · 2024Review
- Resurfacing Hip Arthroplasty Is a Safe and Effective Alternative to Total Hip Arthroplasty in Young Patients: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Antioxidant System and Ions Concentrations After Femoral Neck and Resurfacing Hip Arthroplasty.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Particulate and ion forms of cobalt-chromium challenged preosteoblasts promote osteoclastogenesis and osteolysis in a murine model of prosthesis failure.Journal of biomedical materials research. Part A · 2019Article
- Lessons learnt from early failure of a patient trial with a polymer-on-polymer resurfacing hip arthroplasty.Acta orthopaedica · 2018Article
- How do metal ion levels change over time in hip resurfacing patients? A cohort study.TheScientificWorldJournal · 2014Article
- Serum metal ion concentrations in paediatric patients following total knee arthroplasty using megaprostheses.BioMed research international · 2014Article
- Do ion levels in metal-on-metal hip resurfacing differ from those in metal-on-metal THA at long-term followup?Clinical orthopaedics and related research · 2013Article
- Chromium and cobalt ion concentrations in blood and serum following various types of metal-on-metal hip arthroplasties: a literature overview.Acta orthopaedica · 2013Review
- Patients report improvement in quality of life and satisfaction after hip resurfacing arthroplasty.Clinical orthopaedics and related research · 2013Article
- Metal-on-metal hip resurfacing arthroplasty: an analysis of safety and revision rates.Ontario health technology assessment series · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundModern metal-on-metal hip resurfacing was introduced as a bone-preserving method of joint reconstruction for young and active patients; however, the large diameter of the bearing surfaces is of concern for potentially increased metal ion release. PATIENTS AND
methods71 patients (< 65 years old) were randomly assigned to receive either a resurfacing (R) hip arthroplasty (n = 38) or a conventional metal-on-metal (C) hip arthroplasty (n = 33). Functional outcomes were assessed preoperatively and at 6, 12, and 24 months. Cobalt and chromium blood levels were analyzed preoperatively and at 3, 6, 12, and 24 months.
resultsAll functional outcome scores improved for both groups. At 12 and 24 months, the median UCLA activity score was 8 in the R patients and 7 in the C patients (p < 0.05). At 24 months, OHS was median 16 in C patients and 13 in R patients (p < 0.05). However, in spite of randomization, UCLA scores also appeared to be higher in R patients at baseline. Satisfaction was similar in both groups at 24 months. Cobalt concentrations were statistically significantly higher for R patients only at 3 and 6 months. Chromium levels remained significantly higher for R patients until 24 months. No pseudotumors were encountered in either group. One R patient was revised for early aseptic loosening and in 2 C patients a cup insert was exchanged for recurrent dislocation.
interpretationR patients scored higher on UCLA, OHS, and satisfaction at some time points; however, as for the UCLA, preoperative levels were already in favor of R. The differences, although statistically significant, were of minor clinical importance. Chromium blood levels were statistically significantly higher for R patients at all follow-up measurements, whereas for cobalt this was only observed up to 6 months. The true value of resurfacing hip arthroplasty over conventional metal-on-metal hip arthroplasty will be determined by longer follow-up and a possible shift of balance between their respective (dis)advantages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.