ArticlePloS one2011
GNC and CGA1 modulate chlorophyll biosynthesis and glutamate synthase (GLU1/Fd-GOGAT) expression in Arabidopsis.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 161 citations in OpenAlex.
- Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.Plant physiology · 2013Pooled it
- Genome-wide identification and characterization of GATA transcription factors in Avena sativa L. and expression profiling under salinity stress.Journal of applied genetics · 2026Article
- Regulation of chloroplast biogenesis and differentiation.Journal of experimental botany · 2026Review
- B-GATA factors are required for nitrogen-responsive growth in Physcomitrium patens and Arabidopsis thaliana.The New phytologist · 2026Article
- Cytokinin availability and chloroplast functional lifetime in senescing leaves.Frontiers in plant science · 2026Review
- Genome-wide identification of the YABBY gene family and functional characterization of TaYABBY4A in wheat (Triticum aestivum L.).BMC plant biology · 2025Article
- Genome-wide association mapping reveals genetic loci underlying phenotypic variation in early root vigour improvement induced by osmopriming in Brassica napus L.BMC plant biology · 2025Article
- Increased chloroplast area in the rice bundle sheath through cell-specific perturbation of brassinosteroid signaling.Plant physiology · 2025Article
- The CGA1-SNAT regulatory module potentially contributes to cytokinin-mediated melatonin biosynthesis and drought tolerance in wheat.BMC plant biology · 2025Article
- Transcriptomic and metabolomic analysis of yellow leaf mutant variation inFrontiers in plant science · 2025Article
- Genome-wide characterization and expression analysis of the GATA transcription factor family in response to salt and drought stress in barley (Frontiers in plant science · 2025Article
- Integrative transcriptomic-physiological analysis deciphers nitrogen-mediated carbon reallocation balancing growth and flavonoid metabolism inFrontiers in plant science · 2025Article
- Ubiquitin LigaseInternational journal of molecular sciences · 2024Article
- Glutamine Synthetase and Glutamate Synthase Family Perform Diverse Physiological Functions in Exogenous Hormones and Abiotic Stress Responses inPlants (Basel, Switzerland) · 2024Article
- Identification of quantitative trait loci for lodging and related agronomic traits in soybean (Glycine max [L.] Merr.).BMC genomics · 2024Article
- The Putative GATA Transcription FactorLife (Basel, Switzerland) · 2024Article
- Dual RNA-seq of maize andFrontiers in plant science · 2024Article
- The Genetic Dissection of Nitrogen Use-Related Traits in Flax (International journal of molecular sciences · 2023Article
- The Role of Glutamine Synthetase (GS) and Glutamate Synthase (GOGAT) in the Improvement of Nitrogen Use Efficiency in Cereals.Biomolecules · 2023Review
- Genome-Wide Identification ofInternational journal of molecular sciences · 2023Article
22 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chloroplast development is an important determinant of plant productivity and is controlled by environmental factors including amounts of light and nitrogen as well as internal phytohormones including cytokinins and gibberellins (GA). The paralog GATA transcription factors GNC and CGA1/GNL up-regulated by light, nitrogen and cytokinin while also being repressed by GA signaling. Modifying the expression of these genes has previously been shown to influence chlorophyll content in Arabidopsis while also altering aspects of germination, elongation growth and flowering time. In this work, we also use transgenic lines to demonstrate that GNC and CGA1 exhibit a partially redundant control over chlorophyll biosynthesis. We provide novel evidence that GNC and CGA1 influence both chloroplast number and leaf starch in proportion to their transcript level. GNC and CGA1 were found to modify the expression of chloroplast localized GLUTAMATE SYNTHASE (GLU1/Fd-GOGAT), which is the primary factor controlling nitrogen assimilation in green tissue. Altering GNC and CGA1 expression was also found to modulate the expression of important chlorophyll biosynthesis genes (GUN4, HEMA1, PORB, and PORC). As previously demonstrated, the CGA1 transgenic plants demonstrated significantly altered timing to a number of developmental events including germination, leaf production, flowering time and senescence. In contrast, the GNC transgenic lines we analyzed maintain relatively normal growth phenotypes outside of differences in chloroplast development. Despite some evidence for partial divergence, results indicate that regulation of both GNC and CGA1 by light, nitrogen, cytokinin, and GA acts to modulate nitrogen assimilation, chloroplast development and starch production. Understanding the mechanisms controlling these processes is important for agricultural biotechnology.
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