ArticlePLoS genetics2011
Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont.
Article in PLoS genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.
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116 citing papers in PubMed, 235 citations in OpenAlex.
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- Bacterial symbiont as game changers for Aphis craccivora Koch's fitness and survival across distinct climate types.Scientific reports · 2025Article
- ArtSymbioCyc, a metabolic network database collection dedicated to arthropod symbioses: a case study, the tripartite cooperation inmSystems · 2025Article
- Impact of Species and Developmental Stage on the Bacterial Communities of Aphaenogaster Ants.Current microbiology · 2025Article
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- Comprehensive Analysis of the Fourteen Complete Genome Sequences ofJournal of microbiology and biotechnology · 2024Article
- A complete DNA repair system assembled by two endosymbionts restores heat tolerance of the insect host.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Insect‒microbe symbiosis-based strategies offer a new avenue for the management of insect pests and their transmitted pathogens.Crop health · 2024Review
- Shrinking in the dark: Parallel endosymbiont genome erosions are associated with repeated host transitions to an underground life.Insect science · 2024Article
- microRNA maintains nutrient homeostasis in the symbiont-host interaction.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Discovery of a novelFrontiers in microbiology · 2024Article
- Division of labor within psyllids: metagenomics reveals an ancient dual endosymbiosis with metabolic complementarity in the genusmSystems · 2023Article
- Symbioses shape feeding niches and diversification across insects.Nature ecology & evolution · 2023Article
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- Genomic Characterization of Endosymbiotic Bacteria Associated WithBioinformatics and biology insights · 2023Article
56 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genome sequencing of Buchnera aphidicola BCc from the aphid Cinara cedri, which is the smallest known Buchnera genome, revealed that this bacterium had lost its symbiotic role, as it was not able to synthesize tryptophan and riboflavin. Moreover, the biosynthesis of tryptophan is shared with the endosymbiont Serratia symbiotica SCc, which coexists with B. aphidicola in this aphid. The whole-genome sequencing of S. symbiotica SCc reveals an endosymbiont in a stage of genome reduction that is closer to an obligate endosymbiont, such as B. aphidicola from Acyrthosiphon pisum, than to another S. symbiotica, which is a facultative endosymbiont in this aphid, and presents much less gene decay. The comparison between both S. symbiotica enables us to propose an evolutionary scenario of the transition from facultative to obligate endosymbiont. Metabolic inferences of B. aphidicola BCc and S. symbiotica SCc reveal that most of the functions carried out by B. aphidicola in A. pisum are now either conserved in B. aphidicola BCc or taken over by S. symbiotica. In addition, there are several cases of metabolic complementation giving functional stability to the whole consortium and evolutionary preservation of the actors involved.
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