Evidence map›Paper›PMID 22102583›Full record

ArticleNucleic acids research2012

Mouse Phenome Database (MPD).

Terry P Maddatu, Stephen C Grubb, Carol J Bult, Molly A Bogue

Abstract read
In one paragraph

Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. GMMID: genetically modified mice information database.Database : the journal of biological databases and curation · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Ligature-induced peri-implantitis in mice.Journal of periodontal research · 2015
    Article
  10. Article
  11. Review
  12. Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Methodological considerations for measuring spontaneous physical activity in rodents.American journal of physiology. Regulatory, integrative and comparative physiology · 2014
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Terry P MaddatuThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Stephen C Grubb
Carol J Bult
Molly A Bogue

Funding

MOUSE MODELS OF HEART, LUNG AND BLOOD DISEASEU01HL066611 · NHLBI · JACKSON LABORATORY · PI PETERS, LUANNE L · 2000 to 2007
$25.4M
Translational CoreP30AG038070 · NIA · JACKSON LABORATORY · PI Gary A Churchill · 2010 to 2026
$19.3M
Mouse Phenome ProjectR01DA028420 · NIDA · JACKSON LABORATORY · PI Elissa J Chesler · 2010 to 2026
$9.5M
Shock Center for Aging Research at The Jackson Laborato*P30AG025707 · NIA · JACKSON LABORATORY · PI PAIGEN, BEVERLY J · 2005 to 2009
$4.1M
Phenome ProjectR01MH071984 · NIMH · JACKSON LABORATORY · PI BOGUE, MOLLY A · 2005 to 2009
$1.6M
The Haplotype Map of the Laboratory Mouse GenomeP41HG003057 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DALY, MARK J · 2004 to 2005
$1.3M
NHGRI NIH HHS HG003057NHLBI NIH HHS HL66611NIA NIH HHS AG025707NIA NIH HHS AG038070NIA NIH HHS P30 AG025707NIA NIH HHS P30 AG038070NIDA NIH HHS DA028420NIDA NIH HHS R01 DA028420NIMH NIH HHS MH071984
6 · The paper itself

Abstract

The Mouse Phenome Project was launched a decade ago to complement mouse genome sequencing efforts by promoting new phenotyping initiatives under standardized conditions and collecting the data in a central public database, the Mouse Phenome Database (MPD; http://phenome.jax.org). MPD houses a wealth of strain characteristics data to facilitate the use of the laboratory mouse in translational research for human health and disease, helping alleviate problems involving experimentation in humans that cannot be done practically or ethically. Data sets are voluntarily contributed by researchers from a variety of institutions and settings, or in some cases, retrieved by MPD staff from public sources. MPD maintains a growing collection of standardized reference data that assists investigators in selecting mouse strains for research applications; houses treatment/control data for drug studies and other interventions; offers a standardized platform for discovering genotype-phenotype relationships; and provides tools for hypothesis testing. MPD improvements and updates since our last NAR report are presented, including the addition of new tools and features to facilitate navigation and data mining as well as the acquisition of new data (phenotypic, genotypic and gene expression).

Indexed as

Databases, GeneticPhenotypeAnimalsFemaleGene ExpressionGenetic Association StudiesGenotypeMaleMice

Identifiers

PMID22102583
PMCPMC3245053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.