Evidence map›Paper›PMID 22102180›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2012

Neuro-intensive care of patients with acute CNS infections.

J David Beckham, Kenneth L Tyler

Open access · bronzeAbstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  12. Arbovirus Infections.Continuum (Minneapolis, Minn.) · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

J David BeckhamDepartment of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. david.beckham@ucdenver.edu
Kenneth L Tyler
Denver VA Medical Center · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Vascular stabilization as a broad theraprutic platform for biodefenseU54AI065357 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI SLAYDEN, RICHARD A · 2005 to 2013
$77.5M
Cellular genes and signaling pathways as therapeutic targets for virus-induced CNR01NS076512 · NINDS · UNIVERSITY OF COLORADO DENVER · PI TYLER, KENNETH L. · 2011 to 2014
$1.4M
Mechanisms of Apoptosis in Virus-Infected NeuronsK08AI076518 · NIAID · UNIVERSITY OF COLORADO DENVER · PI BECKHAM, JOHN DAVID · 2008 to 2012
$801k
NIAID NIH HHS K08 AI076518NIAID NIH HHS K08AI076518NIAID NIH HHS U54 AI065357NIAID NIH HHS U54AI065357NINDS NIH HHS R01 NS076512NINDS NIH HHS R01NS076512
6 · The paper itself

Abstract

Infections in the central nervous system (CNS) are caused by a wide range of microorganisms resulting in distinct clinical syndromes including meningitis, encephalitis, and pyogenic infections, such as empyema and brain abscess. Bacterial and viral infections in the CNS can be rapidly fatal and can result in severe disability in survivors. Appropriate identification and acute management of these infections often occurs in a critical care setting and is vital to improving outcomes in this group of patients. This review of diagnosis and management of acute bacterial and viral infections in the CNS provides a general approach to patients with a suspected CNS infection and also provides a more detailed review of the diagnosis and management of patients with suspected bacterial meningitis, viral encephalitis, brain abscess, and subdural empyema.

Indexed as

Critical CareAcute DiseaseCentral Nervous System InfectionsHumansNeurology

Identifiers

PMID22102180
PMCPMC3271160
OpenAlexW2131930101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.