ReviewCurrent rheumatology reports2012
Genetics of systemic sclerosis: an update.
Review in Current rheumatology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of interleukin-1 family cytokines single nucleotide polymorphisms with susceptibility to systemic sclerosis: an independent case-control study and a meta-analysis.Immunologic research · 2016Pooled it
- Trial
- Recent Insights into the Role of DNA Methylation and Histone Modifications in Systemic Sclerosis: A Scoping Review.Diagnostics (Basel, Switzerland) · 2024Article
- Advanced Progress of Histone Deacetylases in Rheumatic Diseases.Journal of inflammation research · 2024Review
- Acute Respiratory Distress Syndrome in a Patient With Systemic Sclerosis: A Case of a Life-Threatening Complication.Cureus · 2024Article
- Genetics of systemic sclerosis.Journal of scleroderma and related disorders · 2020Review
- Glutathione Transferase P1-1 an Enzyme Useful in Biomedicine and as Biomarker in Clinical Practice and in Environmental Pollution.Nutrients · 2019Review
- Risk factors for the development of systemic sclerosis: a systematic review of the literature.Rheumatology advances in practice · 2018Article
- Genetics, Epigenetics, and Genomics of Systemic Sclerosis.Rheumatic diseases clinics of North America · 2015Review
- Involvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis.Protein & cell · 2015Article
- Pathogenesis of Systemic Sclerosis.Frontiers in immunology · 2015Review
- The role of genetics and epigenetics in the pathogenesis of systemic sclerosis.Nature reviews. Rheumatology · 2014Review
- Association of HLA-DPB1 with scleroderma and its clinical features in Chinese population.PloS one · 2014Article
- Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis.ISRN rheumatology · 2013Review
- Latest advances in connective tissue disorders.Therapeutic advances in musculoskeletal disease · 2013Article
- Erythrocyte glutathione transferase: a non-antibody biomarker for systemic sclerosis, which correlates with severity and activity of the disease.Cell death & disease · 2013Article
- The immune pathogenesis of scleroderma: context is everything.Current rheumatology reports · 2013Review
- Is there evidence for vasculitis in systemic sclerosis?Current rheumatology reports · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune cell activation, and fibrosis of the skin and internal organs. Over the past few years, a role for genetics in the susceptibility for SSc has been established. This review aims to provide an update on the progress made in the past year or so within the field of SSc genetics research. This year has been of particular interest due to the publication of a large genome-wide association study, further investigations into gene-gene interactions, and the tendency to validate genetic results in functional models.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.