ArticleNature neuroscience2011
Bidirectional plasticity of cortical pattern recognition and behavioral sensory acuity.
Article in Nature neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.
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Who cites it
111 citing papers in PubMed.
- Olfactory training in patients with Parkinson's disease.PloS one · 2013Trial
- Target-dependent routing of sensory information in the olfactory system.Communications biology · 2026Article
- Experience and behavior modulate piriform cortex odor representation in freely moving mice.iScience · 2026Article
- Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Projection-specific Routing of Odor Information in the Olfactory Cortex.bioRxiv : the preprint server for biology · 2025Article
- Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding.bioRxiv : the preprint server for biology · 2025Article
- Experience-dependent reorganization of inhibitory neuron synaptic connectivity.bioRxiv : the preprint server for biology · 2025Article
- Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex.eLife · 2025Article
- Acquisition of non-olfactory encoding improves odour discrimination in olfactory cortex.Nature communications · 2024Article
- Threat Memory in the Sensory Cortex: Insights from Olfaction.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- Distinct information conveyed to the olfactory bulb by feedforward input from the nose and feedback from the cortex.Nature communications · 2024Article
- The Role of the Stimulus in Olfactory Plasticity.Brain sciences · 2023Review
- Effects of stochastic coding on olfactory discrimination in flies and mice.PLoS biology · 2023Article
- Experience-dependent evolution of odor mixture representations in piriform cortex.PLoS biology · 2023Article
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- Pattern differentiation and tuning shift in human sensory cortex underlie long-term threat memory.Current biology : CB · 2022Article
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- Biological constraints on configural odour mixture perception.The Journal of experimental biology · 2022Article
- Developmental and evolutionary constraints on olfactory circuit selection.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
51 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
Learning to adapt to a complex and fluctuating environment requires the ability to adjust neural representations of sensory stimuli. Through pattern completion processes, cortical networks can reconstruct familiar patterns from degraded input patterns, whereas pattern separation processes allow discrimination of even highly overlapping inputs. Here we show that the balance between pattern separation and completion is experience dependent. Rats given extensive training with overlapping complex odorant mixtures showed improved behavioral discrimination ability and enhanced piriform cortical ensemble pattern separation. In contrast, behavioral training to disregard normally detectable differences between overlapping mixtures resulted in impaired piriform cortical ensemble pattern separation (enhanced pattern completion) and impaired discrimination. This bidirectional effect was not found in the olfactory bulb; it may be due to plasticity within olfactory cortex itself. Thus pattern recognition, and the balance between pattern separation and completion, is highly malleable on the basis of task demands and occurs in concert with changes in perceptual performance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.