Evidence map›Paper›PMID 22101191›Full record

ReviewNanotechnology2011

Nanoparticle-based monitoring of cell therapy.

Chenjie Xu, Luye Mu, Isaac Roes, David Miranda-Nieves, Matthias Nahrendorf, James A Ankrum, Weian Zhao, Jeffrey M Karp

Abstract readReview
In one paragraph

Review in Nanotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
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  6. Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chenjie XuCenter for Regenerative Therapeutics and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.
Luye Mu
Isaac Roes
David Miranda-Nieves
Matthias Nahrendorf
James A Ankrum
Weian Zhao
Jeffrey M Karp

Funding

Engineered Induction of a Stem Cell Homing ResponseR01HL095722 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KARP, JEFFREY MICHAEL · 2010 to 2018
$3.9M
Examining firm adhesion and transmigration of surface engineered MSCsR21HL097172 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KARP, JEFFREY MICHAEL · 2010 to 2011
$470k
Characterization of endogenous stem cells within endosseous woundsR03DE019191 · NIDCR · BRIGHAM AND WOMEN'S HOSPITAL · PI KARP, JEFFREY MICHAEL · 2009 to 2010
$259k
NHLBI NIH HHS HL095722NHLBI NIH HHS HL097172NHLBI NIH HHS R01 HL095722NHLBI NIH HHS R21 HL097172NIDCR NIH HHS DE019191NIDCR NIH HHS R03 DE019191
6 · The paper itself

Abstract

Exogenous cell therapy aims to replace/repair diseased or dysfunctional cells and promises to revolutionize medicine by restoring tissue and organ function. To develop effective cell therapy, the location, distribution and long-term persistence of transplanted cells must be evaluated. Nanoparticle (NP) based imaging technologies have the potential to track transplanted cells non-invasively. Here we summarize the most recent advances in NP-based cell tracking with emphasis on (1) the design criteria for cell tracking NPs, (2) protocols for cell labeling, (3) a comparison of available imaging modalities and their corresponding contrast agents, (4) a summary of preclinical studies on NP-based cell tracking and finally (5) perspectives and future directions.

Indexed as

AnimalsCell- and Tissue-Based TherapyCell TrackingContrast MediaHumansNanoparticlesStaining and LabelingContrast Media

Identifiers

PMID22101191
PMCPMC3334527

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.