ArticleNeuron2011
DISC1: a schizophrenia gene with multiple personalities.
Article in Neuron, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- GSK-3β polymorphism discriminates bipolar disorder and schizophrenia: a systematic meta-analysis.Molecular neurobiology · 2013Pooled it
- Article
- Novel approaches in schizophrenia-from risk factors and hypotheses to novel drug targets.World journal of psychiatry · 2021Review
- Article
- Contrasting characteristic behaviours among common laboratory mouse strains.Royal Society open science · 2019Article
- Role of CACNA1C gene polymorphisms and protein expressions in the pathogenesis of schizophrenia: a case-control study in a Chinese population.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Article
- Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.Molecular psychiatry · 2015Article
- Neurodegenerative aspects in vulnerability to schizophrenia spectrum disorders.Neurotoxicity research · 2014Review
- Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders.Frontiers in behavioral neuroscience · 2014Article
- Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia.Schizophrenia research · 2013Article
- Do genes and environment meet to regulate cerebrospinal fluid dynamics? Relevance for schizophrenia.Frontiers in cellular neuroscience · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two papers address the contribution of DISC1 to neural development and schizophrenia risk in this issue of Neuron. These complementary studies elegantly bridge the gap between genetic and cellular studies of schizophrenia, providing a level of functional validation that is often lacking in the field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.