Evidence map›Paper›PMID 22099390›Full record

ArticleSchizophrenia research2012

SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: data from the CATIE study.

Daniel E Adkins, Amit N Khachane, Joseph L McClay, Karolina Aberg, Jozsef Bukszár, Patrick F Sullivan, Edwin J C G van den Oord

Abstract readLetter
In one paragraph

Article in Schizophrenia research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Ziprasidone versus other atypical antipsychotics for schizophrenia.The Cochrane database of systematic reviews · 2009
    Pooled it
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  9. Molecular Mechanism of theEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
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  11. Study on the Sleep-Improvement Effects ofFoods (Basel, Switzerland) · 2021
    Article
  12. Article
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  14. Article
  15. An Analysis of the Anti-Neuropathic Effects of Qi She Pill Based on Network Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
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  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel E Adkins
Amit N Khachane
Joseph L McClay
Karolina Aberg
Jozsef Bukszár
Patrick F Sullivan
Edwin J C G van den Oord

Funding

Integrating Genomic and Environmental Perspectives on Internalizing DisordersK01MH093731 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI ADKINS, DANIEL E · 2011 to 2015
$649k
NIMH NIH HHS K01 MH093731
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Trials as TopicAntipsychotic AgentsDinoprostoneDouble-Blind MethodFemaleGenetic Association StudiesHumansMaleMental DisordersPharmacogeneticsPolymorphism, Single NucleotidePsychiatric Status Rating ScalesRandomized Controlled Trials as TopicReceptors, Cell SurfaceSignal TransductionTreatment OutcomeAntipsychotic AgentsDinoprostoneReceptors, Cell Surface

Identifiers

PMID22099390
PMCPMC3515657

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.