ArticleActa psychiatrica Scandinavica2012
Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression.
Article in Acta psychiatrica Scandinavica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Sleep and mental disorders: A meta-analysis of polysomnographic research.Psychological bulletin · 2016Pooled it
- Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.Journal of affective disorders · 2013Trial
- Effects of ketamine on circadian rhythm and synaptic homeostasis in patients with treatment-resistant depression: A protocol for mechanistic studies of its rapid and sustained antidepressant actions in humans.Brain and behavior · 2019Article
- A preliminary investigation of the role of slow-wave activity in modulating waking EEG theta as a marker of sleep propensity in major depressive disorder.Journal of affective disorders · 2019Article
- Is Advancing Circadian Rhythm the Mechanism of Antidepressants?Psychiatry investigation · 2019Article
- Article
- An Integrated Model of Slow-Wave Activity and Neuroplasticity Impairments in Major Depressive Disorder.Current psychiatry reports · 2019Review
- High-density EEG characterization of brain responses to auditory rhythmic stimuli during wakefulness and NREM sleep.NeuroImage · 2018Article
- Article
- Effects of oral temazepam on slow waves during non-rapid eye movement sleep in healthy young adults: A high-density EEG investigation.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2016Article
- Effects of partial sleep deprivation on slow waves during non-rapid eye movement sleep: A high density EEG investigation.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2016Article
- The 5α-reductase inhibitor finasteride is not associated with alterations in sleep spindles in men referred for polysomnography.Human psychopharmacology · 2016Article
- Effects of oral temazepam on sleep spindles during non-rapid eye movement sleep: A high-density EEG investigation.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2015Article
- Article
- Astrocytic adenosine: from synapses to psychiatric disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- Medroxyprogesterone acetate is associated with increased sleep spindles during non-rapid eye movement sleep in women referred for polysomnography.Psychoneuroendocrinology · 2013Article
- Altered overnight modulation of spontaneous waking EEG reflects altered sleep homeostasis in major depressive disorder: a high-density EEG investigation.Journal of affective disorders · 2013Article
- Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling.Translational psychiatry · 2013Article
- Effect of five-consecutive-day exposure to an anxiogenic stressor on sleep-wake activity in rats.Frontiers in neurology · 2013Article
- High density electroencephalography in sleep research: potential, problems, future perspective.Frontiers in neurology · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveSleep homeostasis is altered in major depressive disorder (MDD). Pre- to postsleep decline in waking auditory evoked potential (AEP) amplitude has been correlated with sleep slow wave activity (SWA), suggesting that overnight changes in waking AEP amplitude are homeostatically regulated in healthy individuals. This study investigated whether the overnight change in waking AEP amplitude and its relation to SWA is altered in MDD.
methodUsing 256-channel high-density electroencephalography, all-night sleep polysomnography and single-tone waking AEPs pre- and postsleep were collected in 15 healthy controls (HC) and 15 non-medicated individuals with MDD.
resultsN1 and P2 amplitudes of the waking AEP declined after sleep in the HC group, but not in MDD. The reduction in N1 amplitude also correlated with fronto-central SWA in the HC group, but a comparable relationship was not found in MDD, despite equivalent SWA between groups. No pre- to postsleep differences were found for N1 or P2 latencies in either group. These findings were not confounded by varying levels of alertness or differences in sleep variables between groups.
conclusionMDD involves altered sleep homeostasis as measured by the overnight change in waking AEP amplitude. Future research is required to determine the clinical implications of these findings.
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