ArticlePharmacognosy reviews2011
α-glucosidase inhibitors from plants: A natural approach to treat diabetes.
Article in Pharmacognosy reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 206 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
206 citing papers in PubMed, 3 syntheses or guidelines pooled it, 697 citations in OpenAlex.
- The Effect ofNutrients · 2022Pooled it
- Potential Effects of Sweet Potato (International journal of molecular sciences · 2021Pooled it
- The Pharmacological Activity ofBiomolecules · 2020Pooled it
- Postprandial Effects of a Proprietary Milk Protein Hydrolysate Containing Bioactive Peptides in Prediabetic Subjects.Nutrients · 2019Trial
- Acute effect of Clitoria ternatea flower beverage on glycemic response and antioxidant capacity in healthy subjects: a randomized crossover trial.BMC complementary and alternative medicine · 2018Trial
- Postprandial effects of a polyphenolic grape extract (PGE) supplement on appetite and food intake: a randomised dose-comparison trial.Nutrition journal · 2015Trial
- Cryptotanshinone and 15,16-dihydrotanshinone I fromRSC advances · 2026Article
- Design, Synthesis, and In Vitro Evaluation of Pinostrobin-Based Hydrazones as Potent α‑Glucosidase Inhibitors.ACS omega · 2026Article
- Chemical Composition and In Vitro Bioactive Potential of Dried Honeybee (Food science & nutrition · 2026Article
- Synthesis and Anti-Diabetic Evaluation of 2-Phenyl-3Pharmaceutics · 2026Article
- Therapeutic Potential of Kuwanon G: From Bioactivities to Network-Level Mechanisms.Molecules (Basel, Switzerland) · 2026Review
- Antihyperglycemic and Antioxidant Effects ofPharmaceutics · 2026Article
- Metabolite Profiling of Lavender (Pharmaceuticals (Basel, Switzerland) · 2026Article
- From Biodiversity to Biocompatibility: Insights from the Special Issue "Analysis and Biological Evaluation of Bioactive Compounds from Natural Sources-Second Edition".Molecules (Basel, Switzerland) · 2026Article
- Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model.World journal of diabetes · 2026Article
- Phytochemistry and Application of White Mustard (Molecules (Basel, Switzerland) · 2026Review
- Disaccharidase Inhibitory Activity of Thai Plant Extracts.Nutrients · 2026Article
- Design, synthesis, biological evaluation, andRSC advances · 2026Article
- Heterocycle-Tethered Aurones: Synthesis and Evaluation of α-Glucosidase Inhibition.BioMed research international · 2026Article
- Integrated metabolomic, proteomic, and transcriptomic analyses reveal the production of bioactive metabolites and antidiabetic effects in matureFrontiers in plant science · 2026Article
146 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes is a common metabolic disease characterized by abnormally high plasma glucose levels, leading to major complications, such as diabetic neuropathy, retinopathy, and cardiovascular diseases. One of the effective managements of diabetes mellitus, in particular, non-insulin-dependent diabetes mellitus (NIDDM) to decrease postprandial hyperglycemia, is to retard the absorption of glucose by inhibition of carbohydrate hydrolyzing enzymes, such as α-glucosidase and α-amylase, in the digestive organs. α-Glucosidase is the key enzyme catalyzing the final step in the digestive process of carbohydrates. Hence, α-glucosidase inhibitors can retard the liberation of d-glucose from dietary complex carbohydrates and delay glucose absorption, resulting in reduced postprandial plasma glucose levels and suppression of postprandial hyperglycemia. In recent years, many efforts have been made to identify effective α-glucosidase inhibitors from natural sources in order to develop a physiologic functional food or lead compounds for use against diabetes. Many α-glucosidase inhibitors that are phytoconstituents, such as flavonoids, alkaloids, terpenoids,anthocyanins, glycosides, phenolic compounds, and so on, have been isolated from plants. In the present review, we focus on the constituents isolated from different plants having α-glucosidase inhibitory potency along with IC50 values.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.