ArticleNucleic acids research2012
dbDEPC 2.0: updated database of differentially expressed proteins in human cancers.
Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- CSCD2: an integrated interactional database of cancer-specific circular RNAs.Nucleic acids research · 2022Article
- dbGENVOC: database of GENomic Variants of Oral Cancer, with special reference to India.Database : the journal of biological databases and curation · 2021Article
- TarGo: network based target gene selection system for human disease related mouse models.Laboratory animal research · 2019Article
- In silico prediction of cancer immunogens: current state of the art.BMC immunology · 2018Review
- DEXTER: Disease-Expression Relation Extraction from Text.Database : the journal of biological databases and curation · 2018Article
- dbDEPC 3.0: the database of differentially expressed proteins in human cancer with multi-level annotation and drug indication.Database : the journal of biological databases and curation · 2018Article
- CancerPDF: A repository of cancer-associated peptidome found in human biofluids.Scientific reports · 2017Article
- CanProVar 2.0: An Updated Database of Human Cancer Proteome Variation.Journal of proteome research · 2017Article
- Article
- Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal.Oncotarget · 2015Article
- Comprehensive data resources and analytical tools for pathological association of aminoacyl tRNA synthetases with cancer.Database : the journal of biological databases and curation · 2015Article
- Human cancer databases (review).Oncology reports · 2015Review
- Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.Pharmacology & therapeutics · 2013Review
- Integration of proteomics into systems biology of cancer.Wiley interdisciplinary reviews. Systems biology and medicineReview
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Authors and funding
15 authors.
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Abstract
A large amount of differentially expressed proteins (DEPs) have been identified in various cancer proteomics experiments, curation and annotation of these proteins are important in deciphering their roles in oncogenesis and tumor progression, and may further help to discover potential protein biomarkers for clinical applications. In 2009, we published the first database of DEPs in human cancers (dbDEPCs). In this updated version of 2011, dbDEPC 2.0 has more than doubly expanded to over 4000 protein entries, curated from 331 experiments across 20 types of human cancers. This resource allows researchers to search whether their interested proteins have been reported changing in certain cancers, to compare their own proteomic discovery with previous studies, to picture selected protein expression heatmap across multiple cancers and to relate protein expression changes with aberrance in other genetic level. New important developments include addition of experiment design information, advanced filter tools for customer-specified analysis and a network analysis tool. We expect dbDEPC 2.0 to be a much more powerful tool than it was in its first release and can serve as reference to both proteomics and cancer researchers. dbDEPC 2.0 is available at http://lifecenter.sgst.cn/dbdepc/index.do.
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