Evidence map›Paper›PMID 22095352›Full record

ArticleAmerican journal of public health2012

Beyond base pairs to bedside: a population perspective on how genomics can improve health.

Muin J Khoury, Marta Gwinn, M Scott Bowen, W David Dotson

Abstract read
In one paragraph

Article in American journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Using the Delphi method to identify clinicians' perceived importance of pediatric exome sequencing results.Genetics in medicine : official journal of the American College of Medical Genetics · 2020
    Article
  10. Review
  11. Review
  12. Review
  13. Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2015
    Article
  14. Article
  15. Article
  16. Characterizing genetic variants for clinical action.American journal of medical genetics. Part C, Seminars in medical genetics · 2014
    Article
  17. Article
  18. Rethinking our public health genetics research paradigm.American journal of public health · 2013
    Article
  19. Article
  20. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future.Genetics in medicine : official journal of the American College of Medical Genetics · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muin J KhouryOffice of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. muk1@cdc.gov
Marta Gwinn
M Scott Bowen
W David Dotson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A decade after the sequencing of the human genome, the National Human Genome Research Institute announced a strategic plan for genomic medicine. It calls for evaluating the structure and biology of genomes, understanding the biology of disease, advancing the science of medicine, and improving the effectiveness of health care. Fulfilling the promise of genomics urgently requires a population perspective to complement the bench-to-bedside model of translation. A population approach should assess the contribution of genomics to health in the context of social and environmental determinants of disease; evaluate genomic applications that may improve health care; design strategies for integrating genomics into practice; address ethical, legal, and social issues; and measure the population health impact of new technologies.

Indexed as

GenomicsHealth StatusTranslational Research, BiomedicalDelivery of Health CareHumans

Identifiers

PMID22095352
PMCPMC3490552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.