ReviewCurrent psychiatry reports2012
A review of the association between depression and insulin resistance: pitfalls of secondary analyses or a promising new approach to prevention of type 2 diabetes?
Review in Current psychiatry reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Association between impaired glucose metabolism and long-term prognosis at the time of diagnosis of depression: Impaired glucose metabolism as a promising biomarker proposed through a machine-learning approach.European psychiatry : the journal of the Association of European Psychiatrists · 2023Pooled it
- Diabetes in Pregnancy and Risk of Antepartum Depression: A Systematic Review and Meta-Analysis of Cohort Studies.International journal of environmental research and public health · 2020Pooled it
- Incidence and risk of depression associated with diabetes in adults: evidence from longitudinal studies.Community mental health journal · 2015Pooled it
- Depression and risk of mortality in individuals with diabetes: a meta-analysis and systematic review.General hospital psychiatryPooled it
- A decline in inflammation is associated with less depressive symptoms after a dietary intervention in metabolic syndrome patients: a longitudinal study.Nutrition journal · 2014Trial
- Association of metabolic syndrome with depression in US adults: A nationwide cross-sectional study using propensity score-based analysis.Frontiers in public health · 2023Article
- The Association of Metabolic Dysfunction and Mood Across Lifespan Interacts With the Default Mode Network Functional Connectivity.Frontiers in aging neuroscience · 2021Article
- Factors associated with depression, anxiety and stress among patients with diabetes mellitus in primary health care: Many questions, few answers.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2020Article
- Prevalence of gestational diabetes mellitus and associated factors among women attending antenatal care at Gondar town public health facilities, Northwest Ethiopia.BMC pregnancy and childbirth · 2019Article
- Diabetes, Depression, and Cognition: a Recursive Cycle of Cognitive Dysfunction and Glycemic Dysregulation.Current diabetes reports · 2018Review
- Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood.Molecular metabolism · 2016Review
- Role of Sirtuins in Linking Metabolic Syndrome with Depression.Frontiers in cellular neuroscience · 2016Review
- Response to Eskola et al.The American journal of psychiatry · 2015Article
- Toxic stress, inflammation and symptomatology of chronic complications in diabetes.World journal of diabetes · 2015Review
- Depression among older adults with diabetes mellitus.Clinics in geriatric medicine · 2015Review
- Exploring the Link between the Components of Metabolic Syndrome and the Risk of Depression.BioMed research international · 2015Article
- Bidirectional longitudinal study of type 2 diabetes and depression symptoms in black and white church going adults.Journal of diabetes and metabolic disorders · 2015Article
- Accumulation of Major Life Events in Childhood and Adult Life and Risk of Type 2 Diabetes Mellitus.PloS one · 2015Article
- Longitudinal changes in health-related quality of life in normal glucose tolerance, prediabetes and type 2 diabetes: results from the KORA S4/F4 cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Article
- State of the science: depression and type 2 diabetes.Western journal of nursing research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We review the validity of the evidence for an association between depression and the risk of insulin resistance (IR). We describe the potentially plausible biological and behavioral mechanisms that explain how depression increases the risk of IR and consequent overt diabetes. We have identified gaps in the literature to guide future research. Evidence for bidirectional associations between depression and IR is inconsistent. Results showing positive associations between depression and IR are derived from cross-sectional studies, whereas negative findings are typically reported in cohort studies. On the other hand, tentative trial evidence suggests that the effective treatment of depression can improve IR, and that lifestyle programs improve IR and reduce depressive symptoms. These emerging themes could lead to potential new multidisciplinary approaches to preventing diabetes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.