ArticleAmerican heart journal2011
LV twisting and untwisting in HCM: ejection begets filling. Diastolic functional aspects of HCM.
Article in American heart journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- State-of-the-art methodologies used in preclinical studies to assess left ventricular diastolic and systolic function in mice, pitfalls and troubleshooting.Frontiers in cardiovascular medicine · 2023Review
- Cardiac Imaging in the Athlete: Shrinking the "Gray Zone".Current treatment options in cardiovascular medicine · 2020Review
- Altered regional myocardial velocities by tissue phase mapping and feature tracking in pediatric patients with hypertrophic cardiomyopathy.Pediatric radiology · 2020Article
- Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 2: Pluridisciplinary perspective on their genetic and molecular origins.Journal of molecular and cellular cardiology · 2019Review
- Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 1: Pluridisciplinary perspective on their hemodynamics and morphomechanics.Journal of molecular and cellular cardiology · 2019Article
- Morphomechanic phenotypic variability of sarcomeric cardiomyopathies: A multifactorial polygenic perspective.Journal of molecular and cellular cardiology · 2019Review
- Stretch your heart-but not too far: The role of titin mutations in dilated cardiomyopathy.The Journal of thoracic and cardiovascular surgery · 2018Review
- The new era of whole-exome sequencing in congenital heart disease: brand-new insights into rare pathogenic variants.Journal of thoracic disease · 2018Article
- Challenges and Controversies in Hypertrophic Cardiomyopathy: Clinical, Genomic and Basic Science Perspectives.Revista espanola de cardiologia (English ed.) · 2018Article
- Clarification on the role of LV untwisting in LV "relaxation" and diastolic filling.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Genomic translational research: Paving the way to individualized cardiac functional analyses and personalized cardiology.International journal of cardiology · 2017Review
- Cardiovascular magnetic resonance evaluation of symptomatic severe aortic stenosis: association of circumferential myocardial strain and mortality.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017Article
- Calcific Aortic Valve Disease: Part 1--Molecular Pathogenetic Aspects, Hemodynamics, and Adaptive Feedbacks.Journal of cardiovascular translational research · 2016Review
- Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions.Journal of cardiovascular translational research · 2015Review
- Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2.Journal of cardiovascular translational research · 2015Article
- Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1.Journal of cardiovascular translational research · 2015Review
- Vortex formation time is not an index of ventricular function.Journal of cardiovascular translational research · 2015Review
- Evaluation of right and left ventricular diastolic filling.Journal of cardiovascular translational research · 2013Review
- Right and left ventricular diastolic flow field: why are measured intraventricular pressure gradients small?Revista espanola de cardiologia (English ed.) · 2013Article
- Right and left ventricular diastolic pressure-volume relations: a comprehensive review.Journal of cardiovascular translational research · 2013Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Conventional and emerging concepts on mechanisms by which hypertrophic cardiomyopathy (HCM) engenders diastolic dysfunction are surveyed. A shift from familiar left ventricular (LV) diastolic function approaches to large-scale (twist-untwist) and small-scale (titin unfolding-refolding, etc.) wall rebound models, incorporating interaction and dynamic distortions and rearrangements of myofiber sheets and ultrastructural constituents, is suggested. Such an emerging new paradigm of diastolic dynamics, emphasizing the relationship of myofiber sheet and ultraconstituent distortion to LV mechanics and end-systolic shape, might clarify intricate patterns of early diastolic rebound and suction, needed for LV filling in many of the polymorphic phenotypes of HCM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.