Evidence map›Paper›PMID 22092522›Full record

ReviewFEMS microbiology ecology2012

Application of phylogenetic microarrays to interrogation of human microbiota.

Oleg Paliy, Richard Agans

Abstract readReview
In one paragraph

Review in FEMS microbiology ecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Methods for exploring the faecal microbiome of premature infants: a review.Maternal health, neonatology and perinatology · 2021
    Review
  4. Review
  5. Microbiota in cerebrovascular disease: A key player and future therapeutic target.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Oleg PaliyDepartment of Biochemistry and Molecular Biology, Wright State University, Dayton, OH 45435, USA. oleg.paliy@wright.edu
Richard Agans
Wright State University · US

Funding

Using Affymetrix Microflora array to study microflora composition in children witR21AT003423 · NCCIH · WRIGHT STATE UNIVERSITY · PI PALIY, OLEG · 2008 to 2009
$395k
Quantitative measurements of intestinal metabolites in healthy and IBS childrenR03HD065575 · NICHD · WRIGHT STATE UNIVERSITY · PI PALIY, OLEG · 2010 to 2011
$143k
NCCIH NIH HHS AT003423NCCIH NIH HHS R21 AT003423NICHD NIH HHS HD065575NICHD NIH HHS R03 HD065575
6 · The paper itself

Abstract

Human-associated microbiota is recognized to play vital roles in maintaining host health, and it is implicated in many disease states. While the initial surge in the profiling of these microbial communities was achieved with Sanger and next-generation sequencing, many oligonucleotide microarrays have also been developed recently for this purpose. Containing probes complementary to small ribosomal subunit RNA gene sequences of community members, such phylogenetic arrays provide direct quantitative comparisons of microbiota composition among samples and between sample groups. Some of the developed microarrays including PhyloChip, Microbiota Array, and HITChip can simultaneously measure the presence and abundance of hundreds and thousands of phylotypes in a single sample. This review describes the currently available phylogenetic microarrays that can be used to analyze human microbiota, delineates the approaches for the optimization of microarray use, and provides examples of recent findings based on microarray interrogation of human-associated microbial communities.

Indexed as

BacteriaFecesGene Expression ProfilingHumansIliumMetagenomeMicrobial ConsortiaOligonucleotide Array Sequence AnalysisOropharynxPhylogenyRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID22092522
PMCPMC3237809
OpenAlexW1997872347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.