Evidence map›Paper›PMID 22091839›Full record

ReviewFEMS microbiology reviews2012

Recent progress in Bacillus subtilis sporulation.

Douglas Higgins, Jonathan Dworkin

Open access · bronzeAbstract readReview
In one paragraph

Review in FEMS microbiology reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 264 papers.

0numbers the graph read from it
0cells of the map it votes in
264citing papers in PubMed
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

264 citing papers in PubMed, 490 citations in OpenAlex.

  1. Article
  2. MclX modulates the process of mother cell lysis by SpoIIID inApplied and environmental microbiology · 2026
    Article
  3. A lipid cue drives the subcellular localization of a self-inserting bacterial transmembrane protein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Molecular insights into the promiscuous ApThe Journal of biological chemistry · 2026
    Article
  6. Article
  7. Optimizing submerged cultivation of Bacillus velezensis for endospore production and formulation.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  8. Review
  9. Article
  10. New insights into the structure-based mechanism ofApplied and environmental microbiology · 2026
    Article
  11. Optical analysis of bacterial metabolic activity and spore germination via formazan formation.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Effects ofMicroorganisms · 2026
    Article
  17. Article
  18. Evolutionary bioenergetics of sporulation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Sepsis as CNS-governed metabolic triage.Frontiers in immunology · 2026
    Review
  20. The Mechanisms ofMicroorganisms · 2025
    Review

204 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Douglas HigginsDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Jonathan Dworkin
Columbia University · US

Funding

Peptidoglycan synthesis during sporulationR01GM081368 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DWORKIN, JONATHAN · 2008 to 2012
$1.6M
NIGMS NIH HHS R01 GM081368NIGMS NIH HHS R01GM081368-04
6 · The paper itself

Abstract

The Gram-positive bacterium Bacillus subtilis can initiate the process of sporulation under conditions of nutrient limitation. Here, we review some of the last 5 years of work in this area, with a particular focus on the decision to initiate sporulation, DNA translocation, cell-cell communication, protein localization and spore morphogenesis. The progress we describe has implications not only just for the study of sporulation but also for other biological systems where homologs of sporulation-specific proteins are involved in vegetative growth.

Indexed as

Gene Expression Regulation, BacterialSignal TransductionBacillus subtilisModels, BiologicalProtein TransportSpores, BacterialStress, Physiological

Identifiers

PMID22091839
PMCPMC3237856
OpenAlexW2112404034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.