ArticleMolecular biology international2011
Evasion of Host Defence by Leishmania donovani: Subversion of Signaling Pathways.
Article in Molecular biology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed.
- Comprehensive proteomic analysis of autophagosomes derived from Leishmania-infected macrophages.PloS one · 2023Article
- Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts.Marine drugs · 2021Review
- LmjF.36.3850, a novel hypothetical Leishmania major protein, contributes to the infection.Immunology · 2021Article
- Super enhancer-mediated transcription of miR146a-5p drives M2 polarization during Leishmania donovani infection.PLoS pathogens · 2021Article
- Circulatory microRNAs: promising non-invasive prognostic and diagnostic biomarkers for parasitic infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Review
- RNA-Seq Revealed Expression of Many Novel Genes Associated WithFrontiers in cellular and infection microbiology · 2019Article
- Evaluation of Different Concentrations of Imatinib on the Viability ofAdvanced biomedical research · 2019Article
- Edwardsiella piscicida Type III Secretion System Effector EseK Inhibits Mitogen-Activated Protein Kinase Phosphorylation and Promotes Bacterial Colonization in Zebrafish Larvae.Infection and immunity · 2018Article
- Countervailing, time-dependent effects on host autophagy promotes intracellular survival ofThe Journal of biological chemistry · 2018Article
- Liposomal Elongation Factor-1α Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis.Frontiers in immunology · 2018Article
- Role of Mast Cells in clearance of Leishmania through extracellular trap formation.Scientific reports · 2017Article
- MicroRNA expression profiling of Leishmania donovani-infected host cells uncovers the regulatory role of MIR30A-3p in host autophagy.Autophagy · 2016Article
- Down-Regulation of TLR and JAK/STAT Pathway Genes Is Associated with Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis in NK Cells from Patients Infected with Leishmania mexicana.PLoS neglected tropical diseases · 2016Article
- Leishmania donovani Exploits Myeloid Cell Leukemia 1 (MCL-1) Protein to Prevent Mitochondria-dependent Host Cell Apoptosis.The Journal of biological chemistry · 2016Article
- The Mitogen-Activated Protein Kinase (MAPK) Pathway: Role in Immune Evasion by Trypanosomatids.Frontiers in microbiology · 2016Review
- Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages.PLoS pathogens · 2014Article
- Immunotherapy and targeted therapies in treatment of visceral leishmaniasis: current status and future prospects.Frontiers in immunology · 2014Review
- Trypanosoma cruzi parasites fight for control of the JAK-STAT pathway by disarming their host.JAK-STAT · 2014Review
- Signaling networks in Leishmania macrophages deciphered through integrated systems biology: a mathematical modeling approach.Systems and synthetic biology · 2013Article
- MicroRNA expression profile in human macrophages in response to Leishmania major infection.PLoS neglected tropical diseases · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protozoan parasites of the genus Leishmania are responsible for causing a variety of human diseases known as leishmaniasis, which range from self-healing skin lesions to severe infection of visceral organs that are often fatal if left untreated. Leishmania donovani (L. donovani), the causative agent of visceral leishmaniasis, exemplifys a devious organism that has developed the ability to invade and replicate within host macrophage. In fact, the parasite has evolved strategies to interfere with a broad range of signaling processes in macrophage that includes Protein Kinase C, the JAK2/STAT1 cascade, and the MAP Kinase pathway. This paper focuses on how L. donovani modulates these signaling pathways that favour its survival and persistence in host cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.