ArticleMolecular biology international2011
Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo.
Article in Molecular biology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 20 citations in OpenAlex.
- Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus).BMC genetics · 2020Article
- Molecular characterization of MHC II DRB3 gene of swamp- and riverine-type water buffaloes.Journal of advanced veterinary and animal research · 2019Article
- Sequence diversity of MHC class-IIJournal of genetics · 2018Article
- Association of SNP variants of MHC Class II DRB gene with thermo-physiological traits in tropical goats.Tropical animal health and production · 2017Article
- A comprehensive mapping of the structure and gene organisation in the sheep MHC class I region.BMC genomics · 2015Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was conducted to study the diversity of MHC-DRB3 alleles in Indian cattle and buffalo breeds. Previously reported BoLA-DRB exon 2 alleles of Indian Zebu cattle, Bos taurus cattle, buffalo, sheep, and goats were analyzed for the identities and divergence among various allele sequences. Comparison of predicted amino acid residues of DRB3 exon 2 alleles with similar alleles from other ruminants revealed considerable congruence in amino acid substitution pattern. These alleles showed a high degree of nucleotide and amino acid polymorphism at positions forming peptide-binding regions. A higher rate of nonsynonymous substitution was detected at the peptide-binding regions, indicating that BoLA-DRB3 allelic sequence evolution was driven by positive selection.
Identifiers
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Registered trials
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