Evidence map›Paper›PMID 22091225›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2011

The association of hypertriglyceridemic waist phenotype with type 2 diabetes mellitus among individuals with first relative history of diabetes.

Massoud Amini, Ahmad Esmaillzadeh, Marzieh Sadeghi, Najmahe Mehvarifar, Marzieh Amini, Maryam Zare

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Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

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13citing papers in PubMed
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3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Hypertriglyceridemic waist phenotype in primary health care: comparison of two cutoff points.Diabetes, metabolic syndrome and obesity : targets and therapy · 2017
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Massoud AminiProfessor of Endocrinolgy, Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Ahmad Esmaillzadeh
Marzieh Sadeghi
Najmahe Mehvarifar
Marzieh Amini
Maryam Zare

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntropometric measures with biochemical indicators have been used as screening tools for metabolic abnormalities in adolescents and adults. A few studies have assessed the relation of EWET (Enlarge waist Elevated triglyceride) phenotype with diabetes, especially among individuals with first relative history of diabetes. This study aimed to evaluate the association of EWET phenotype with diabetes among individuals with family history of diabetes.

methodsAntropometric and biochemical measurments were evaluated in a population - based cross - sectional study of 332 male and 991 female Isfahani adults aged 35-55 year. The EWET phenotype was defined as serum trigcylglycerol concentrations ≥ 150 mg/dl and concurrent waist circumference (WC) ≥ 88 cm in females and ≥ 102 cm in males.

resultsThe prevalence of EWET phenotype was respectively 9.6% and 23.6% among male and female. Individuals with the phenotype had significantly higher BMI and WHR (waist to hip ratio) as compared to other groups. After control for age and physical activity, male with EWET phenotype were significantly more likely to have high serum triglyceride levels (p < 0.001), cholesterol (p < 0.001). Even after additional control for BMI, the significant associations remained except for low HDL Cholestrol. Female with EWET phenotype had significantly adverse metabolic risks as compared to other groups, either before or after control for BMI (p < 0.001). Individuals with the phenotype were more likely to have diabetes (both gender) and (IGT) Impaired Glucose Tolerance (female only).

conclusionsOur results showed that EWET phenotype has significantly associated with diabetes. This phenotype could be used for early identification of diabetes and IGT.

Indexed as

Enlarge waist Elevated triglycerideIGTObesity and Antropometric

Identifiers

PMID22091225
PMCPMC3214297

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